ENSDARG00000030490


Danio rerio

Features
Gene ID: ENSDARG00000030490
  
Biological name :sptb
  
Synonyms : spectrin, beta, erythrocytic / sptb
  
Possible biological names infered from orthology : P11277
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 38566717
Gene end: 38599022
  
Corresponding Affymetrix probe sets: Dr.10652.1.S1_at (Zebrafish Array)   NM_131525_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040626
Ensembl peptide - ENSDARP00000113965
NCBI entrez gene - 58040     See in Manteia.
RefSeq - NM_131525
RefSeq - XM_005158850
RefSeq - XM_005158851
RefSeq Peptide - NP_571600
swissprot - F1QQE5
ZFIN ID - ZDB-GENE-000906-1
Ensembl - ENSDARG00000030490
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPTBENSGALG00000036805Gallus gallus
 SPTBENSG00000070182Homo sapiens
 SptbENSMUSG00000021061Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sptbn1 / spectrin, beta, non-erythrocytic 1 / Q01082* / Q62261* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG0000010288357
sptbn2 / spectrin, beta, non-erythrocytic 2 / O15020*ENSDARG0000005395656
SPTBN4 / si:ch73-262h23.4 / Q9H254* / spectrin beta, non-erythrocytic 4*ENSDARG0000009262429
sptbn5 / spectrin, beta, non-erythrocytic 5 / Q9NRC6*ENSDARG0000009768327
sptan1 / spectrin alpha, non-erythrocytic 1 / SPTA1* / Q13813* / P08032* / P16546* / P02549* / spectrin alpha, erythrocytic 1* / Spectrin alpha chain, erythrocytic 1 * / Spectrin alpha chai...ENSDARG0000001923122
si:dkey-27p18.5 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG0000006862416
actn3b / actinin alpha 3b / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000000143111
actn1 / actinin, alpha 1 / P12814* / Q7TPR4* / Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA.*ENSDARG0000000721911
actn3a / actinin alpha 3a / ACTN3* / Q08043* / O88990* / Alpha-actinin-3 * / actinin alpha 3 (gene/pseudogene)*ENSDARG0000001375511
actn2b / actinin, alpha 2b / ACTN2* / P35609* / Q9JI91* / actinin alpha 2* / Alpha-actinin-2 *ENSDARG0000007109011
actn4 / actinin, alpha 4 / O43707*ENSDARG0000009978611
si:ch73-262h23.4 / Q9H254* / SPTBN4* / spectrin beta, non-erythrocytic 4*ENSDARG000001119428
si:zfos-1837d3.1 / Q62261* / Q01082* / SPTBN1* / spectrin beta, non-erythrocytic 1* / Spectrin beta chain, non-erythrocytic 1 *ENSDARG000001054283


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001605  Pleckstrin homology domain, spectrin-type
 IPR001715  Calponin homology domain
 IPR001849  Pleckstrin homology domain
 IPR002017  Spectrin repeat
 IPR011993  PH-like domain superfamily
 IPR016343  Spectrin, beta subunit
 IPR018159  Spectrin/alpha-actinin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0048821 erythrocyte development IMP
 biological_processGO:0051693 actin filament capping IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008091 spectrin IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
NCAM signaling for neurite out-growth
Interaction between L1 and Ankyrins
RAF/MAP kinase cascade
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle dilated , abnormal
Show

 ZFA:0000471 atrium atrium dilated , abnormal
Show

 ZFA:0000529 kidney kidney increased size , abnormal
kidney hyperplastic , abnormal
kidney has extra parts of type erythroid progenitor cell , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte shape , abnormal
nucleate erythrocyte binucleate , abnormal
nucleate erythrocyte absent , abnormal
nucleate erythrocyte spherical , abnormal
nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte teardrop-shaped , abnormal
nucleate erythrocyte nucleus structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr