ENSDARG00000019278


Danio rerio

Features
Gene ID: ENSDARG00000019278
  
Biological name :GNB4
  
Synonyms : GNB4 / G protein subunit beta 4
  
Possible biological names infered from orthology : guanine nucleotide binding protein (G protein), beta 4 / P29387 / Q9HAV0
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 5300405
Gene end: 5311253
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000010862
swissprot - E7F0T7
Ensembl - ENSDARG00000019278
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNB4ENSGALG00000008983Gallus gallus
 GNB4ENSG00000114450Homo sapiens
 Gnb4ENSMUSG00000027669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gnb4b / guanine nucleotide binding protein (G protein), beta polypeptide 4b / GNB4* / Q9HAV0* / G protein subunit beta 4*ENSDARG0000011538389
gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*ENSDARG0000003535788
gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*ENSDARG0000009045486
gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*ENSDARG0000010437286
gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000435869
gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*ENSDARG0000000269661
gnb5b / Q6PBY0 / guanine nucleotide binding protein (G protein), beta 5b / GNB5* / O14775* / P62881* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000005537748
gnb5a / A1L271 / guanine nucleotide binding protein (G protein), beta 5a / GNB5* / P62881* / O14775* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*ENSDARG0000009968547
wdr47a / WD repeat domain 47a / WDR47* / Q8CGF6* / O94967* / WD repeat domain 47*ENSDARG0000007813626
wdr47b / WD repeat domain 47b / WDR47* / O94967* / WD repeat domain 47*ENSDARG0000009975724


Protein motifs (from Interpro)
Interpro ID Name
 IPR001632  G-protein, beta subunit
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016346  Guanine nucleotide-binding protein, beta subunit
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA


Pathways (from Reactome)
Pathway description
G-protein activation
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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