Manteia

ENSDARG00000115383

Danio rerio

Features

Gene ID:	ENSDARG00000115383

Biological name :	gnb4b

Synonyms :	gnb4b / guanine nucleotide binding protein (G protein), beta polypeptide 4b

Possible biological names infered from orthology :	GNB4 / G protein subunit beta 4 / guanine nucleotide binding protein (G protein), beta 4 / P29387 / Q9HAV0

Species:	Danio rerio

Chr. number:	11
Strand:	1
Band:
Gene start:	44226200
Gene end:	44447359

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000146896 Ensembl peptide - ENSDARP00000147599 NCBI entrez gene - 492811 See in Manteia. swissprot - Q5U3U8 ZFIN ID - ZDB-GENE-041114-167 Ensembl - ENSDARG00000115383

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
GNB4	ENSGALG00000008983	Gallus gallus
GNB4	ENSG00000114450	Homo sapiens
Gnb4	ENSMUSG00000027669	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
gnb1b / guanine nucleotide binding protein (G protein), beta polypeptide 1b / GNB1* / P62874* / P62873* / G protein subunit beta 1* / guanine nucleotide binding protein (G protein), beta 1*	ENSDARG00000104372	90
gnb2 / guanine nucleotide binding protein (G protein), beta polypeptide 2 / P62880* / P62879* / G protein subunit beta 2* / guanine nucleotide binding protein (G protein), beta 2*	ENSDARG00000035357	89
gnb1a / Q6PH57 / guanine nucleotide binding protein (G protein), beta polypeptide 1a / GNB1* / P62873* / G protein subunit beta 1*	ENSDARG00000090454	89
gnb3a / guanine nucleotide binding protein (G protein), beta polypeptide 3a / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*	ENSDARG00000004358	72
GNB4 / G protein subunit beta 4 / Q9HAV0*	ENSDARG00000019278	65
gnb3b / guanine nucleotide binding protein (G protein), beta polypeptide 3b / GNB3* / Q61011* / P16520* / G protein subunit beta 3* / guanine nucleotide binding protein (G protein), beta 3*	ENSDARG00000002696	63
gnb5b / Q6PBY0 / guanine nucleotide binding protein (G protein), beta 5b / GNB5* / O14775* / P62881* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*	ENSDARG00000055377	53
gnb5a / A1L271 / guanine nucleotide binding protein (G protein), beta 5a / GNB5* / P62881* / O14775* / G protein subunit beta 5* / guanine nucleotide binding protein (G protein), beta 5*	ENSDARG00000099685	52
wdr47a / WD repeat domain 47a / WDR47* / Q8CGF6* / O94967* / WD repeat domain 47*	ENSDARG00000078136	27
wdr47b / WD repeat domain 47b / WDR47* / O94967* / WD repeat domain 47*	ENSDARG00000099757	26

Protein motifs (from Interpro)

Interpro ID	Name
IPR001632	G-protein, beta subunit
IPR001680	WD40 repeat
IPR015943	WD40/YVTN repeat-like-containing domain superfamily
IPR016346	Guanine nucleotide-binding protein, beta subunit
IPR017986	WD40-repeat-containing domain
IPR019775	WD40 repeat, conserved site
IPR020472	G-protein beta WD-40 repeat

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA

Pathways (from Reactome)

Pathway description

G-protein activation

ADP signalling through P2Y purinoceptor 12

G beta:gamma signalling through PI3Kgamma

Prostacyclin signalling through prostacyclin receptor

Adrenaline,noradrenaline inhibits insulin secretion

Ca2+ pathway

G alpha (q) signalling events

G alpha (12/13) signalling events

G beta:gamma signalling through PLC beta

G alpha (s) signalling events

ADP signalling through P2Y purinoceptor 1

G alpha (i) signalling events

G alpha (z) signalling events

Thromboxane signalling through TP receptor

Vasopressin regulates renal water homeostasis via Aquaporins

Thrombin signalling through proteinase activated receptors (PARs)

Presynaptic function of Kainate receptors

Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000056831	gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*	/ complex / reaction
ENSDARG00000009480	pdcl / phosducin-like / Q13371* / Q9DBX2* / Phosducin-like protein *	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr