ENSDARG00000019341


Danio rerio

Features
Gene ID: ENSDARG00000019341
  
Biological name :gpc1a
  
Synonyms : glypican 1a / gpc1a
  
Possible biological names infered from orthology : glypican 1 / GPC1 / P35052 / Q9QZF2
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 15507218
Gene end: 15548201
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000106138
swissprot - Q1LXM6
ZFIN ID - ZDB-GENE-051120-147
Ensembl - ENSDARG00000019341
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPC1ENSGALG00000040316Gallus gallus
 GPC1ENSG00000063660Homo sapiens
 Gpc1ENSMUSG00000034220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpc1b / glypican 1b / GPC1* / P35052* / glypican 1*ENSDARG0000009058552
gpc6a / glypican 6a / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010315642
gpc4 / glypican 4 / O75487* / P51655*ENSDARG0000001547237
gpc6b / glypican 6b / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010421937
gpc5a / glypican 5a / GPC5* / P78333* / glypican 5*ENSDARG0000010364723
gpc2 / glypican 2 / Q8N158*ENSDARG0000010421723
gpc5b / glypican 5bENSDARG0000002458820
gpc3 / glypican 3 / P51654* / Q8CFZ4*ENSDARG0000003219919
CU467828.1ENSDARG0000007408216


Protein motifs (from Interpro)
Interpro ID Name
 IPR001863  Glypican
 IPR015502  Glypican-1
 IPR019803  Glypican, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Signaling by ROBO receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased functionality , exacerbated
liver has fewer parts of type intrahepatic bile duct , exacerbated
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 ZFA:0000208 gall bladder gall bladder decreased size , abnormal
gall bladder lacks parts or has fewer parts of type cell , abnormal
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 ZFA:0001100 hepatic duct hepatic duct morphology , abnormal
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 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct decreased functionality , abnormal
intrahepatic bile duct decreased length , exacerbated
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 ZFA:0005170 extrahepatic duct extrahepatic duct decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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