ENSDARG00000032199


Danio rerio

Features
Gene ID: ENSDARG00000032199
  
Biological name :gpc3
  
Synonyms : glypican 3 / gpc3
  
Possible biological names infered from orthology : P51654 / Q8CFZ4
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 31176952
Gene end: 31465905
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142166
NCBI entrez gene - 387365     See in Manteia.
swissprot - Q6V9Y8
ZFIN ID - ZDB-GENE-031212-1
Ensembl - ENSDARG00000032199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPC3ENSGALG00000006087Gallus gallus
 GPC3ENSG00000147257Homo sapiens
 Gpc3ENSMUSG00000055653Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpc5a / glypican 5a / GPC5* / P78333* / glypican 5*ENSDARG0000010364731
gpc5b / glypican 5bENSDARG0000002458827
gpc6a / glypican 6a / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010315620
CU467828.1ENSDARG0000007408219
gpc1b / glypican 1b / GPC1* / P35052* / glypican 1*ENSDARG0000009058519
gpc6b / glypican 6b / GPC6* / Q9Y625* / glypican 6*ENSDARG0000010421919
gpc4 / glypican 4 / O75487* / P51655*ENSDARG0000001547218
gpc1a / glypican 1a / GPC1* / P35052* / Q9QZF2* / glypican 1*ENSDARG0000001934118
gpc2 / glypican 2 / Q8N158*ENSDARG0000010421713


Protein motifs (from Interpro)
Interpro ID Name
 IPR001863  Glypican
 IPR015501  Glypican-3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IGI
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
HS-GAG biosynthesis
HS-GAG degradation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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