response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulus response to abiotic stimulus detection of stimulus establishment of localization response to external stimulusresponse to external stimulus response to abiotic stimulusresponse to abiotic stimulus detection of stimulusdetection of stimulus establishment of localizationestablishment of localization transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activity ion binding transmembrane transporter activitytransmembrane transporter activity ion bindingion binding membrane membrane membrane membrane membrane membrane membrane membrane membrane membrane membranemembrane