ENSDARG00000033029


Danio rerio

Features
Gene ID: ENSDARG00000033029
  
Biological name :pkd1b
  
Synonyms : pkd1b / polycystic kidney disease 1b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 21697540
Gene end: 21748008
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127250
NCBI entrez gene - 565697     See in Manteia.
RefSeq - XM_021480305
swissprot - U3JAI2
ZFIN ID - ZDB-GENE-100707-2
Ensembl - ENSDARG00000033029
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pkd1a / polycystic kidney disease 1a / PKD1* / P98161* / polycystin 1, transient receptor potential channel interacting*ENSDARG0000003041727
pkd1l2a / polycystic kidney disease 1 like 2a / Pkd1l2*ENSDARG000001053449
pkd1l2b / polycystic kidney disease 1 like 2b / Pkd1l2*ENSDARG000001012147
pkd2 / Q6IVV8 / polycystic kidney disease 2 / Q13563* / O35245* / Polycystin-2 * / polycystin 2, transient receptor potential cation channel*ENSDARG000000140983
pkd2l1 / polycystic kidney disease 2-like 1 / A2A259* / Q9P0L9* / Polycystic kidney disease 2-like 1 protein * / polycystin 2 like 1, transient receptor potential cation channel*ENSDARG000000225033
pkd1l2b / polycystic kidney disease 1 like 2b / Pkd1l2*ENSDARG000000881213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000434  Polycystic kidney disease type 1 protein
 IPR000601  PKD domain
 IPR001024  PLAT/LH2 domain
 IPR002859  PKD/REJ-like domain
 IPR013122  Polycystin cation channel, PKD1/PKD2
 IPR013783  Immunoglobulin-like fold
 IPR014010  REJ domain
 IPR022409  PKD/Chitinase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001946 lymphangiogenesis IGI
 biological_processGO:0032965 regulation of collagen biosynthetic process IGI
 biological_processGO:0050982 detection of mechanical stimulus IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005262 calcium channel activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
Show

 ZFA:0001094 whole organism whole organism curved dorsal , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage chondrocyte circular , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
Show

 ZFA:0005110 thoracic duct thoracic duct absent , abnormal
thoracic duct malformed , abnormal
Show

 ZFA:0009395 vascular lymphangioblast vascular lymphangioblast cell migration process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr