ENSDARG00000028222


Danio rerio

Features
Gene ID: ENSDARG00000028222
  
Biological name :itgb8
  
Synonyms : integrin, beta 8 / itgb8
  
Possible biological names infered from orthology : integrin subunit beta 8 / P26012
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 2275019
Gene end: 2307722
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000117882
Ensembl peptide - ENSDARP00000152742
swissprot - F1QN46
ZFIN ID - ZDB-GENE-071213-3
Ensembl - ENSDARG00000028222
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGB8ENSGALG00000010875Gallus gallus
 ITGB8ENSG00000105855Homo sapiens
 Itgb8ENSMUSG00000025321Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itgb5 / integrin, beta 5 / P18084* / integrin subunit beta 5*ENSDARG0000001294237
itgb6 / integrin, beta 6 / P18564* / Q9Z0T9* / integrin subunit beta 6*ENSDARG0000000249435
itgb3b / integrin beta 3b / ITGB3* / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSDARG0000004507034
itgb3a / integrin beta 3a / ITGB3* / P05106* / AC068234.1* / integrin subunit beta 3*ENSDARG0000005676734
itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*ENSDARG0000007186332
itgb2 / integrin, beta 2 / Itgb2l* / P05107* / Q3UV74* / integrin subunit beta 2* / Integrin beta-2-like protein *ENSDARG0000001693931
itgb1b.1 / integrin, beta 1b.1ENSDARG0000005323231
itgb4 / integrin, beta 4 / A2A863* / P16144* / integrin subunit beta 4*ENSDARG0000002850729
itgb7 / integrin, beta 7 / P26010* / P26011* / integrin subunit beta 7*ENSDARG0000004431828
itgb1b.1 / itgb1b.2 / integrin, beta 1b.2ENSDARG0000002268924
itgb1b / integrin, beta 1b / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010448422
CABZ01058721.1 / ITGB1* / P05556* / integrin subunit beta 1*ENSDARG0000010992910
itgbl1 / integrin, beta-like 1 / O95965* / Q8VDV0* / integrin subunit beta like 1* / Integrin beta-like protein 1 *ENSDARG000000409857


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR012896  Integrin beta subunit, tail
 IPR013111  EGF-like domain, extracellular
 IPR015442  Integrin beta-8 subunit
 IPR015812  Integrin beta subunit
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IGI
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001935 endothelial cell proliferation IGI
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hemorrhagic , abnormal
brain hydrocephalic , abnormal
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 ZFA:0000099 brain vasculature brain vasculature broken , abnormal
brain vasculature has fewer parts of type central artery , abnormal
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 ZFA:0000604 ventral aorta ventral aorta has fewer parts of type vascular associated smooth muscle cell , abnormal
Show

 ZFA:0005003 pharyngeal vasculature pharyngeal vasculature has fewer parts of type vascular associated smooth muscle cell , abnormal
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 ZFA:0005020 central artery central artery morphology , abnormal
central artery irregular spatial pattern , abnormal
central artery decreased length , abnormal
central artery direction , abnormal
central artery unlumenized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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