ENSDARG00000029075


Danio rerio

Features
Gene ID: ENSDARG00000029075
  
Biological name :pfkfb4b
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / pfkfb4b
  
Possible biological names infered from orthology : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 / PFKFB4 / Q16877 / Q6DTY7
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 39993605
Gene end: 40029423
  
Corresponding Affymetrix probe sets: Dr.13097.1.S1_at (Zebrafish Array)   NM_198816_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000094007
Ensembl peptide - ENSDARP00000080101
NCBI entrez gene - 386663     See in Manteia.
RefSeq - XM_005166025
RefSeq - NM_198816
RefSeq Peptide - NP_942111
swissprot - F6NXI0
swissprot - F6NIB1
ZFIN ID - ZDB-GENE-031031-4
Ensembl - ENSDARG00000029075
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PFKFB4ENSGALG00000002099Gallus gallus
 PFKFB4ENSG00000114268Homo sapiens
 Pfkfb4ENSMUSG00000025648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pfkfb4a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*ENSDARG0000005554081
pfkfb1 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 / P16118* / P70266*ENSDARG0000003714067
si:dkey-96f10.1 / P16118* / P70266* / PFKFB1* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1*ENSDARG0000007445767
pfkfb3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*ENSDARG0000000195363
pfkfb2b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000000203762
pfkfb2a / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a / PFKFB2* / O60825* / Gm29427* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2*ENSDARG0000002384061


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000029075 pfkfb4b / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b / PFKFB4* / Q6DTY7* / Q16877* / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4*  / complex






 

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