ENSGALG00000002099


Gallus gallus

Features
Gene ID: ENSGALG00000002099
  
Biological name :PFKFB4
  
Synonyms : 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 / PFKFB4
  
Possible biological names infered from orthology : Q16877 / Q6DTY7
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 1394466
Gene end: 1434613
  
Corresponding Affymetrix probe sets: Gga.17198.1.S1_x_at (Chicken Array)   GgaAffx.1348.1.A1_at (Chicken Array)   GgaAffx.25392.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044351
Ensembl peptide - ENSGALP00000054523
Ensembl peptide - ENSGALP00000046747
Ensembl peptide - ENSGALP00000003271
NCBI entrez gene - 100859653     See in Manteia.
RefSeq - XM_015292807
RefSeq - XM_015292801
RefSeq - XM_015292803
RefSeq - XM_015292804
RefSeq - XM_015292805
RefSeq - XM_003641962
RefSeq - XM_004944391
RefSeq - XM_004944392
RefSeq - XM_004944393
RefSeq - XM_004944394
RefSeq - XM_015292800
swissprot - A0A1D5PNS9
swissprot - A0A1D5P252
swissprot - F1P0K7
swissprot - A0A1D5NVH6
Ensembl - ENSGALG00000002099
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pfkfb4aENSDARG00000055540Danio rerio
 pfkfb4bENSDARG00000029075Danio rerio
 PFKFB4ENSG00000114268Homo sapiens
 Pfkfb4ENSMUSG00000025648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PFKFB3 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 / Q16875*ENSGALG0000004036953
PFKFB2 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 / O60825* / Gm29427*ENSGALG0000000111750


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR003094  Fructose-2,6-bisphosphatase
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR013079  6-phosphofructo-2-kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006000 fructose metabolic process IEA
 biological_processGO:0006003 fructose 2,6-bisphosphate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0046835 carbohydrate phosphorylation IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003873 6-phosphofructo-2-kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002099 PFKFB4 / 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 / Q16877* / Q6DTY7*  / complex






 

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