Manteia

ENSDARG00000030933

Danio rerio

Features

Gene ID:	ENSDARG00000030933

Biological name :	ksr1b

Synonyms :	kinase suppressor of ras 1b / ksr1b

Possible biological names infered from orthology :	kinase suppressor of ras 1 / KSR1 / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA. / Q61097 / Q8IVT5

Species:	Danio rerio

Chr. number:	15
Strand:	-1
Band:
Gene start:	31070603
Gene end:	31147322

Corresponding Affymetrix probe sets:	Dr.23913.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000048102 Ensembl peptide - ENSDARP00000128013 Ensembl peptide - ENSDARP00000128838 Ensembl peptide - ENSDARP00000129721 NCBI entrez gene - 556779 See in Manteia. swissprot - F1QFX8 swissprot - X1WCR6 swissprot - X1WF34 swissprot - X1WHK8 ZFIN ID - ZDB-GENE-040724-45 Ensembl - ENSDARG00000030933

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ksr1a / kinase suppressor of ras 1a / KSR1* / Q61097* / Q8IVT5* / kinase suppressor of ras 1* / Mus musculus kinase suppressor of ras 1 (Ksr1), transcript variant 2, mRNA.*	ENSDARG00000068714	65
ksr2 / kinase suppressor of ras 2 / Q6VAB6*	ENSDARG00000094526	47
braf / B-Raf proto-oncogene, serine/threonine kinase / P15056* / P28028* / Serine/threonine-protein kinase B-raf *	ENSDARG00000017661	18
raf1b / Raf-1 proto-oncogene, serine/threonine kinase b / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000059406	16
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000096415	16
araf / A-Raf proto-oncogene, serine/threonine kinase / P04627* / P10398* / Serine/threonine-protein kinase A-Raf *	ENSDARG00000054533	14
si:ch73-263f13.1 / KSR2* / Q6VAB6* / kinase suppressor of ras 2*	ENSDARG00000094172	6
raf1a / Raf-1 proto-oncogene, serine/threonine kinase a / RAF1* / Q99N57* / P04049* / Raf-1 proto-oncogene, serine/threonine kinase* / Mus musculus v-raf-leukemia viral onco 1 (Raf1), trans...	ENSDARG00000102328	4

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR008271	Serine/threonine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR025561	Kinase suppressor of RAS, SAM-like domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006468	protein phosphorylation	IBA
biological_process	GO:0007265	Ras protein signal transduction	IBA
biological_process	GO:0035556	intracellular signal transduction	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IBA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IBA
cellular_component	GO:0016020	membrane	IBA
molecular_function	GO:0004672	protein kinase activity	IBA
molecular_function	GO:0004871	obsolete signal transducer activity	IBA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

RAF activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr