ENSDARG00000032976


Danio rerio

Features
Gene ID: ENSDARG00000032976
  
Biological name :cmlc1
  
Synonyms : cardiac myosin light chain-1 / cmlc1
  
Possible biological names infered from orthology : Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA. / MYL4 / myosin light chain 4 / P12829
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 64167620
Gene end: 64168415
  
Corresponding Affymetrix probe sets: Dr.8379.1.S1_at (Zebrafish Array)   NM_131692_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000048394
NCBI entrez gene - 64671     See in Manteia.
RefSeq - NM_131692
RefSeq Peptide - NP_571767
swissprot - B0R0F7
ZFIN ID - ZDB-GENE-030522-1
Ensembl - ENSDARG00000032976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYL4ENSGALG00000000585Gallus gallus
 MYL4ENSG00000198336Homo sapiens
 Myl4ENSMUSG00000061086Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myl4 / myosin, light chain 4, alkali; atrial, embryonic / P12829* / myosin light chain 4* / Mus musculus myosin, light polypeptide 4 (Myl4), transcript variant 2, mRNA.*ENSDARG0000001151973
myl13 / myosin, light chain 13ENSDARG0000004224569
zgc:163073 / MYL3* / P08590* / P09542* / myosin light chain 3*ENSDARG0000009971263
myl1 / myosin, light chain 1, alkali; skeletal, fast / P05977* / P05976* / myosin light chain 1* / Myosin light chain 1/3, skeletal muscle isoform *ENSDARG0000001419657
zgc:153867 / MYL6* / MYL6B* / P60660* / P14649* / Q60605* / Q8CI43* / myosin light chain 6* / myosin light chain 6B* / myosin, light polypeptide 6, alkali, smooth muscle and non-muscle*ENSDARG0000003373856
myl6 / myosin, light chain 6, alkali, smooth muscle and non-muscle / MYL6B* / Q8CI43* / P14649* / P60660* / Q60605* / myosin light chain 6* / myosin light chain 6B* / myosin, light polypept...ENSDARG0000000849455
mylz3 / myosin, light polypeptide 3, skeletal muscle / MYL1* / P05977* / P05976* / myosin light chain 1* / Myosin light chain 1/3, skeletal muscle isoform *ENSDARG0000001744146


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0048738 cardiac muscle tissue development IMP
 biological_processGO:0055005 ventricular cardiac myofibril assembly IMP
 biological_processGO:0055015 ventricular cardiac muscle cell development IMP
 biological_processGO:0060047 heart contraction IMP
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle striated muscle myosin thick filament absent , abnormal
cardiac ventricle sarcomere immature , abnormal
cardiac ventricle contractility , abnormal
cardiac ventricle decreased diameter , abnormal
cardiac ventricle collapsed , abnormal
cardiac ventricle increased volume , abnormal
cardiac ventricle increased size , abnormal
cardiac ventricle decreased contractility , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart decreased strength , abnormal
heart quality , abnormal
Show

 ZFA:0000471 atrium atrium contractility , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001315 atrioventricular canal atrioventricular canal decreased amount , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell sarcomere increased length , abnormal
cardiac muscle cell shape , abnormal
cardiac muscle cell increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr