ENSDARG00000034117


Danio rerio

Features
Gene ID: ENSDARG00000034117
  
Biological name :rarga
  
Synonyms : Q91392 / rarga / retinoic acid receptor gamma a
  
Possible biological names infered from orthology : P13631 / P18911 / RARG / retinoic acid receptor gamma
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 35847200
Gene end: 35963735
  
Corresponding Affymetrix probe sets: Dr.194.1.S1_at (Zebrafish Array)   Dr.23544.1.S1_s_at (Zebrafish Array)   NM_131339_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000112380
Ensembl peptide - ENSDARP00000123094
Ensembl peptide - ENSDARP00000049550
NCBI entrez gene - 30606     See in Manteia.
RefSeq - NM_131339
RefSeq Peptide - NP_571414
swissprot - A2BGD4
swissprot - Q91392
ZFIN ID - ZDB-GENE-980526-531
Ensembl - ENSDARG00000034117
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RARGENSG00000172819Homo sapiens
 RargENSMUSG00000001288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rargb / retinoic acid receptor, gamma b / RARG* / P13631* / retinoic acid receptor gamma*ENSDARG0000005400372
rarab / Q7ZTI3 / retinoic acid receptor, alpha b / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000003489363
raraa / Q90271 / retinoic acid receptor, alpha a / RARA* / P11416* / P10276* / retinoic acid receptor alpha*ENSDARG0000005678362
thraa / Q98867 / thyroid hormone receptor alpha a / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000000015126
thrb / Q9PVE4 / thyroid hormone receptor beta / P10828* / P37242*ENSDARG0000002116326
thrab / thyroid hormone receptor alpha b / THRA* / P63058* / P10827* / thyroid hormone receptor, alpha*ENSDARG0000005265426
nr1h3 / nuclear receptor subfamily 1, group H, member 3 / Q13133*ENSDARG0000009843925
nr1h4 / nuclear receptor subfamily 1, group H, member 4 / Q60641* / Q96RI1* / Bile acid receptor *ENSDARG0000005774123
vdrb / Q1L673 / vitamin D receptor b / VDR* / P48281* / P11473* / vitamin D receptor* / vitamin D (1,25-dihydroxyvitamin D3) receptor*ENSDARG0000007072121
nr1i2 / nuclear receptor subfamily 1, group I, member 2 / O54915* / O75469*ENSDARG0000002976620
nr1h5 / nuclear receptor subfamily 1, group H, member 5ENSDARG0000003104619
vdra / vitamin D receptor a / VDR* / P11473* / vitamin D receptor*ENSDARG0000009948311
CABZ01088036.1 / VDR* / P11473* / vitamin D receptor*ENSDARG0000011292310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003078  Retinoic acid receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0048384 retinoic acid receptor signaling pathway IEA
 biological_processGO:0060037 pharyngeal system development IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0003708 retinoic acid receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0001608 pharyngeal arch 5 pharyngeal arch 5 immature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000004697 rxrgb / Q6DHP9 / retinoid X receptor, gamma b / RXRG* / P28705* / P48443* / retinoid X receptor gamma* / Retinoic acid receptor RXR-gamma *  / complex
 ENSDARG00000030449 crabp2b / cellular retinoic acid binding protein 2, b / CRABP2* / P22935* / P29373* / cellular retinoic acid binding protein 2*  / complex / reaction
 ENSDARG00000073978 crabp2a / cellular retinoic acid binding protein 2, a / CRABP2* / P22935* / P29373* / cellular retinoic acid binding protein 2*  / complex / reaction






 

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