ENSDARG00000038068


Danio rerio

Features
Gene ID: ENSDARG00000038068
  
Biological name :ddx5
  
Synonyms : ddx5 / DEAD (Asp-Glu-Ala-Asp) box helicase 5
  
Possible biological names infered from orthology : DEAD-box helicase 5 / Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (Ddx5), transcript variant 3, mRNA. / P17844
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 25269861
Gene end: 25275403
  
Corresponding Affymetrix probe sets: Dr.664.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000055491
Ensembl peptide - ENSDARP00000132531
Ensembl peptide - ENSDARP00000122701
Ensembl peptide - ENSDARP00000121201
NCBI entrez gene - 322206     See in Manteia.
RefSeq - NM_212612
RefSeq - NM_001309525
RefSeq Peptide - NP_001296454
RefSeq Peptide - NP_997777
swissprot - Q6NWH7
swissprot - E9QG17
swissprot - B0JZJ1
swissprot - A0A0R4IDH0
swissprot - F1Q5L6
ZFIN ID - ZDB-GENE-030131-925
Ensembl - ENSDARG00000038068
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX5ENSGALG00000003532Gallus gallus
 DDX5ENSG00000108654Homo sapiens
 Ddx5ENSMUSG00000020719Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-156n14.5 / DDX17* / Q92841* / DEAD-box helicase 17*ENSDARG0000001087367
ddx42 / DEAD (Asp-Glu-Ala-Asp) box helicase 42 / Q810A7* / Q86XP3* / DEAD-box helicase 42* / ATP-dependent RNA helicase DDX42 *ENSDARG0000003792834
ddx43 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 / DDX53* / Q9NXZ2* / Q86TM3* / DEAD-box helicase 43* / DEAD-box helicase 53*ENSDARG0000002261433


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
mRNA Splicing - Major Pathway
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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