ENSGALG00000003532


Gallus gallus

Features
Gene ID: ENSGALG00000003532
  
Biological name :DDX5
  
Synonyms : DDX5 / DEAD-box helicase 5
  
Possible biological names infered from orthology : Mus musculus DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (Ddx5), transcript variant 3, mRNA. / P17844
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 6959486
Gene end: 6966959
  
Corresponding Affymetrix probe sets: Gga.4548.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005576
Ensembl peptide - ENSGALP00000062413
Ensembl peptide - ENSGALP00000061209
Ensembl peptide - ENSGALP00000058801
Ensembl peptide - ENSGALP00000050033
NCBI entrez gene - 395629     See in Manteia.
RefSeq - XM_015279871
RefSeq - NM_204827
RefSeq Peptide - NP_990158
swissprot - A0A1L1RJ74
swissprot - A0A1D5PBA9
swissprot - A0A1L1RUB6
swissprot - Q9W744
swissprot - A0A1L1RQZ1
Ensembl - ENSGALG00000003532
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddx5ENSDARG00000038068Danio rerio
 DDX5ENSG00000108654Homo sapiens
 Ddx5ENSMUSG00000020719Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX17 / DEAD-box helicase 17 / Q501J6* / Q92841* / Probable ATP-dependent RNA helicase DDX17 *ENSGALG0000003736069
DDX42 / ATP-dependent RNA helicase DDX42 / Q810A7* / Q86XP3* / DEAD-box helicase 42*ENSGALG0000000058136
DDX53* / DDX43* / Q86TM3* / Q9NXZ2* / DEAD-box helicase 53* / DEAD-box helicase 43*ENSGALG0000001592834


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR012587  RNA helicase p68 repeat
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033488  RNA helicase p68 (DDX5)


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000380 alternative mRNA splicing, via spliceosome IEA
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0001837 epithelial to mesenchymal transition IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009299 mRNA transcription IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator IEA
 biological_processGO:0060765 regulation of androgen receptor signaling pathway IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 cellular_componentGO:0071141 SMAD protein complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003724 RNA helicase activity IEA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035500 MH2 domain binding IEA
 molecular_functionGO:0036002 pre-mRNA binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA
 molecular_functionGO:0046332 SMAD binding IEA
 molecular_functionGO:0050681 androgen receptor binding IEA
 molecular_functionGO:0070412 R-SMAD binding IEA
 molecular_functionGO:0070878 primary miRNA binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors
mRNA Splicing - Major Pathway
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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