ENSDARG00000045298


Danio rerio

Features
Gene ID: ENSDARG00000045298
  
Biological name :wipf2a
  
Synonyms : WAS/WASL interacting protein family, member 2a / wipf2a
  
Possible biological names infered from orthology : Q6PEV3 / Q8TF74 / WAS/WASL interacting protein family member 2 / WIPF2
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 11844123
Gene end: 11890001
  
Corresponding Affymetrix probe sets: Dr.12755.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000144952
Ensembl peptide - ENSDARP00000150073
Ensembl peptide - ENSDARP00000075985
Ensembl peptide - ENSDARP00000135667
NCBI entrez gene - 563976     See in Manteia.
RefSeq - XM_005155759
swissprot - A0A0R4INU0
swissprot - F1R8X0
ZFIN ID - ZDB-GENE-121219-6
Ensembl - ENSDARG00000045298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WIPF2ENSGALG00000037633Gallus gallus
 WIPF2ENSG00000171475Homo sapiens
 Wipf2ENSMUSG00000038013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
wipf2b / WAS/WASL interacting protein family, member 2b / WIPF2* / Q8TF74* / WAS/WASL interacting protein family member 2*ENSDARG0000000671253
sb:cb649 / WIPF3* / A6NGB9* / WAS/WASL interacting protein family member 3*ENSDARG0000003624527


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR028294  WAS/WASL-interacting protein family member 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000015149 wasa / Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a / WAS* / P70315* / P42768* / Wiskott-Aldrich syndrome*  / reaction
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction
 ENSDARG00000079475 nckipsd / NCK interacting protein with SH3 domain / Q9NZQ3*  / reaction
 ENSDARG00000075369 nck1b / NCK adaptor protein 1b / NCK1* / P16333* / Q99M51* / NCK adaptor protein 1* / Cytoplasmic protein NCK1 *  / reaction
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction
 ENSDARG00000044573 cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *  / reaction






 

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