ENSDARG00000056803


Danio rerio

Features
Gene ID: ENSDARG00000056803
  
Biological name :ap1s1
  
Synonyms : adaptor-related protein complex 1, sigma 1 subunit / ap1s1
  
Possible biological names infered from orthology : AP-1 complex subunit sigma-1A / P61966 / P61967
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 26245061
Gene end: 26263206
  
Corresponding Affymetrix probe sets: Dr.18735.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000152182
Ensembl peptide - ENSDARP00000091884
Ensembl peptide - ENSDARP00000113731
Ensembl peptide - ENSDARP00000142911
Ensembl peptide - ENSDARP00000151157
NCBI entrez gene - 393279     See in Manteia.
RefSeq - NM_001328014
RefSeq - NM_001328016
RefSeq - NM_200309
RefSeq Peptide - NP_001314945
RefSeq Peptide - NP_001314943
RefSeq Peptide - NP_956603
swissprot - Q6NSP1
swissprot - A0A1D5NSU3
swissprot - F1Q5Z2
ZFIN ID - ZDB-GENE-040426-1119
Ensembl - ENSDARG00000056803
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AP1S1ENSG00000106367Homo sapiens
 Ap1s1ENSMUSG00000004849Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ap1s2 / adaptor-related protein complex 1, sigma 2 subunitENSDARG0000005850482
ap1s3b / adaptor-related protein complex 1, sigma 3 subunit, b / AP1S3* / Q96PC3* / Q7TN05* / AP-1 complex subunit sigma-3 * / adaptor related protein complex 1 sigma 3 subunit*ENSDARG0000002796668
ap1s3a / adaptor-related protein complex 1, sigma 3 subunit, a / AP1S3* / Q96PC3* / adaptor related protein complex 1 sigma 3 subunit*ENSDARG0000011043967
CABZ01102528.1ENSDARG0000009899049
ap2s1 / adaptor-related protein complex 2, sigma 1 subunit / P53680* / P62743* / AP-2 complex subunit sigma *ENSDARG0000002696743
ap4s1 / adaptor-related protein complex 4, sigma 1 subunit / Q9WVL1* / Q9Y587* / AP-4 complex subunit sigma-1 *ENSDARG0000005422037
AP1S2 / adaptor related protein complex 1 sigma 2 subunit / P56377*ENSDARG0000011322523


Protein motifs (from Interpro)
Interpro ID Name
 IPR000804  Clathrin adaptor complex, small chain
 IPR011012  Longin-like domain superfamily
 IPR016635  Adaptor protein complex, sigma subunit
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030198 extracellular matrix organization IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0008565 protein transporter activity IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain distended , abnormal
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 ZFA:0000135 notochord notochord kinked , abnormal
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 ZFA:0000368 integument integument disorganized , abnormal
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 ZFA:0000778 spinal cord interneuron spinal cord interneuron decreased amount , abnormal
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 ZFA:0001058 caudal fin caudal fin disorganized , abnormal
caudal fin basal lamina disorganized , abnormal
caudal fin basal lamina distributed , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0009091 melanocyte melanocyte decreased pigmentation , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / complex
 ENSDARG00000096454 ap1m2 / adaptor-related protein complex 1, mu 2 subunit / Q9Y6Q5*  / complex
 ENSDARG00000045618 clta / clathrin, light chain A / P09496*  / complex
 ENSDARG00000053122 clvs2 / Q5SPP0 / clavesin 2 / CLVS1* / Q8IUQ0* / clavesin 1*  / complex
 ENSDARG00000020621 ap1b1 / adaptor-related protein complex 1, beta 1 subunit / O35643* / Q10567* / Mus musculus adaptor protein complex AP-1, beta 1 subunit (Ap1b1), transcript variant 4, mRNA.*  / complex
 ENSDARG00000096249 ap1m1 / adaptor-related protein complex 1, mu 1 subunit / Q9BXS5*  / complex
 ENSDARG00000090716 cltcb / clathrin, heavy chain b (Hc) / CLTC* / Q00610* / clathrin heavy chain*  / complex






 

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