ENSDARG00000057911


Danio rerio
actinACTC1conservedsitebindingfamilyactin-likeregulationgeneexpressionmesenchymemigrationcytoplasmlamellipodiumfilopodiumcellbodynucleotideatpstriatedmusclecontraction

Features
Gene ID: ENSDARG00000057911
  
Biological name :ACTC1
  
Synonyms : ACTC1 / zgc:86709
  
Possible biological names infered from orthology : actin, alpha, cardiac muscle 1 / P68032 / P68033
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 9970786
Gene end: 9980318
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000075110
NCBI entrez gene - 570210     See in Manteia.
swissprot - Q6IQL9
ZFIN ID - ZDB-GENE-040625-35
Ensembl - ENSDARG00000057911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTC1ENSGALG00000009844Gallus gallus
 ACTC1ENSG00000159251Homo sapiens
 Actc1ENSMUSG00000068614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
acta1a / actin, alpha 1a, skeletal muscleENSDARG00000036371100
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG00000042535100
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG00000076126100
acta2 / actin, alpha 2, smooth muscle, aorta / P62736* / P62737* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*ENSDARG0000004518099
acta1b / actin, alpha 1b, skeletal muscleENSDARG0000005561899
acta2 / actc1b / actin, alpha, cardiac muscle 1b / ACTC1* / P68032* / actin, alpha, cardiac muscle 1*ENSDARG0000009919799
actc1c / actin, alpha, cardiac muscle 1c / ACTG2* / P63268* / P63267* / Actin, gamma-enteric smooth muscle * / actin, gamma 2, smooth muscle, enteric*ENSDARG0000007911197
actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...ENSDARG0000003774693
actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...ENSDARG0000003787093
actr1 / ARP1 actin related protein 1, centractin / Q8R5C5* / ACTR1B* / P42025* / Beta-centractin * / ARP1 actin related protein 1 homolog B*ENSDARG0000001161153
si:ch211-241j12.3ENSDARG0000004396352


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site


Gene Ontology (GO)
organic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processanatomical structure developmenttissue migrationorganic substance metabolic processorganic substance metabolic processanatomical structure developmentanatomical structure developmenttissue migrationtissue migration
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingsmall molecule bindingsmall molecule bindingion bindingion bindingcarbohydrate derivativecarbohydrate derivative bindingdrug bindingdrug binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0090131 mesenchyme migration ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0044297 cell body ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000057911 ACTC1 / zgc:86709 / P68032* / P68033* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000099197 acta2 / actc1b / actin, alpha, cardiac muscle 1b / ACTC1* / P68032* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000042535 actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000045180 acta2 / actin, alpha 2, smooth muscle, aorta / P62736* / P62737* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*  / -






 

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