ENSDARG00000099197


Danio rerio

Features
Gene ID: ENSDARG00000099197
  
Biological name :actc1b
  
Synonyms : acta2 / actc1b / actin, alpha, cardiac muscle 1b
  
Possible biological names infered from orthology : ACTC1 / actin, alpha, cardiac muscle 1 / P68032 / P68033
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 117024
Gene end: 125091
  
Corresponding Affymetrix probe sets: AFFX-Dr-acta1-3_at (Zebrafish Array)   AFFX-Dr-acta1-5_x_at (Zebrafish Array)   AFFX-Dr-acta1-M_at (Zebrafish Array)   Dr.815.1.S1_at (Zebrafish Array)   Dr.815.1.S1_x_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000066429
Ensembl peptide - ENSDARP00000130083
NCBI entrez gene - 58114     See in Manteia.
swissprot - Q6DHS1
swissprot - Q9I8V1
ZFIN ID - ZDB-GENE-000322-1
ZFIN ID - ZDB-GENE-030131-1229
Ensembl - ENSDARG00000099197
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACTC1ENSGALG00000009844Gallus gallus
 ACTC1ENSG00000159251Homo sapiens
 Actc1ENSMUSG00000068614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
acta1a / actin, alpha 1a, skeletal muscleENSDARG0000003637199
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000004253599
acta1b / actin, alpha 1b, skeletal muscleENSDARG0000005561899
ACTC1 / zgc:86709 / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000005791199
actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*ENSDARG0000007612699
acta2 / actin, alpha 2, smooth muscle, aorta / P62736* / P62737* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*ENSDARG0000004518098
actc1c / actin, alpha, cardiac muscle 1c / ACTG2* / P63268* / P63267* / Actin, gamma-enteric smooth muscle * / actin, gamma 2, smooth muscle, enteric*ENSDARG0000007911198
actb1 / Q7ZVI7 / actin, beta 1 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...ENSDARG0000003774692
actb2 / Q7ZVF9 / actin, beta 2 / ACTB* / ACTG1* / POTEJ* / P60709* / P0CG39* / P60710* / P63260* / P63261* / actin beta* / actin gamma 1* / POTE ankyrin domain family member J* / Actin, cyt...ENSDARG0000003787092
actr1 / ARP1 actin related protein 1, centractin / Q8R5C5* / ACTR1B* / P42025* / Beta-centractin * / ARP1 actin related protein 1 homolog B*ENSDARG0000001161153
si:ch211-241j12.3ENSDARG0000004396351


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR020902  Actin/actin-like conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008015 blood circulation IMP
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0060047 heart contraction IMP
 biological_processGO:0090131 mesenchyme migration ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0044297 cell body ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000005 artery artery increased diameter , abnormal
Show

 ZFA:0001089 myoseptum myoseptum intracellular part aggregated , abnormal
Show

 ZFA:0001338 intestine intestine smooth muscle non-contractile , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle intracellular part aggregated , abnormal
skeletal muscle disorganized , abnormal
skeletal muscle mitochondrion increased amount , abnormal
skeletal muscle sarcomere increased thickness , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell broken , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000057911 ACTC1 / zgc:86709 / P68032* / P68033* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000099197 acta2 / actc1b / actin, alpha, cardiac muscle 1b / ACTC1* / P68032* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000042535 actc1a / actin, alpha, cardiac muscle 1a / ACTC1* / P68032* / P68033* / actin, alpha, cardiac muscle 1*  / -
 ENSDARG00000045180 acta2 / actin, alpha 2, smooth muscle, aorta / P62736* / P62737* / Actin, aortic smooth muscle Actin, aortic smooth muscle, intermediate form*  / -






 

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