ENSDARG00000058821


Danio rerio

Features
Gene ID: ENSDARG00000058821
  
Biological name :sema5a
  
Synonyms : sema5a / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
  
Possible biological names infered from orthology : Q13591 / semaphorin 5A
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 16393302
Gene end: 16706981
  
Corresponding Affymetrix probe sets: Dr.1101.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137400
Ensembl peptide - ENSDARP00000150854
Ensembl peptide - ENSDARP00000144320
Ensembl peptide - ENSDARP00000076198
NCBI entrez gene - 561295     See in Manteia.
RefSeq - XM_005162619
RefSeq - XM_021470194
RefSeq - NM_001271670
RefSeq Peptide - NP_001258599
swissprot - A0A286YBG6
swissprot - A0A0R4IMM9
swissprot - F1R9L1
ZFIN ID - ZDB-GENE-030131-8969
Ensembl - ENSDARG00000058821
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEMA5AENSGALG00000028685Gallus gallus
 Q13591ENSG00000112902Homo sapiens
 Sema5aENSMUSG00000022231Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sema5ba / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba / SEMA5B* / Q60519* / Q9P283* / semaphorin 5B*ENSDARG0000006147155
sema5bb / sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb / SEMA5B* / Q60519* / Q9P283* / semaphorin 5B*ENSDARG0000007564854
sema6dl / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like / SEMA6D* / Q76KF0* / Q8NFY4* / semaphorin 6D*ENSDARG0000001153322
sema6e / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E / Q9WTM3* / SEMA6C* / Q9H3T2* / semaphorin 6C* / sema domain, transmembrane domain (TM), and cytopla...ENSDARG0000000018921
sema6ba / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba / Q9H3T3* / SEMA6B* / O54951* / semaphorin 6B* / sema domain, transmembrane domain (TM), and cytop...ENSDARG0000003662620
sema6d / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D / Q9WTM3* / SEMA6C* / Q9H3T2* / semaphorin 6C* / sema domain, transmembrane domain (TM), and cytopla...ENSDARG0000000274819
sema6bb / sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Bb / Q9H3T3* / SEMA6B* / O54951* / semaphorin 6B* / sema domain, transmembrane domain (TM), and cytop...ENSDARG0000006197618
sema7a / semaphorin 7A / O75326* / Q9QUR8* / semaphorin 7A (John Milton Hagen blood group)*ENSDARG0000007870713
si:ch211-113g11.6ENSDARG0000007044212


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001627  Sema domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR027231  Semaphorin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0048675 axon extension IMP
 biological_processGO:0050919 negative chemotaxis IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0038191 neuropilin binding IBA


Pathways (from Reactome)
Pathway description
Other semaphorin interactions
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001056 myotome myotome CaP motoneuron hypoplastic , abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032990 plxnb3 / plexin B3 / Q9QY40* / Q9ULL4*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr