ENSDARG00000061986


Danio rerio
domaingtpasetbc1d2bintracellularactivityrab-gtpase-tbcpleckstrinhomologyph-likesuperfamilyproteintransportregulationvesiclefusionactivationendomembraneactivatorrabbinding

Features
Gene ID: ENSDARG00000061986
  
Biological name :tbc1d2b
  
Synonyms : tbc1d2b / TBC1 domain family, member 2B
  
Possible biological names infered from orthology : Q3U0J8 / Q9UPU7
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 25592082
Gene end: 25646806
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000083499
Ensembl peptide - ENSDARP00000125459
NCBI entrez gene - 100330777     See in Manteia.
swissprot - E7FB23
swissprot - H0WF28
ZFIN ID - ZDB-GENE-100922-148
Ensembl - ENSDARG00000061986
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TBC1D2BENSGALG00000003322Gallus gallus
 Q9UPU7ENSG00000167202Homo sapiens
 Q3U0J8ENSMUSG00000037410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbc1d2 / TBC1 domain family, member 2 / B1AVH7* / Q9BYX2* / TBC1 domain family member 2A *ENSDARG0000007130436
tbc1d9 / TBC1 domain family, member 9 (with GRAM domain) / Q3UYK3* / Q6ZT07* / TBC1 domain family member 9*ENSDARG0000005990017
tbc1d9 / TBC1 domain family, member 9 (with GRAM domain) / Q66K14* / TBC1D9B* / TBC1 domain family member 9B*ENSDARG0000004362716
B0R0W9 / TBC1D8B / si:dkey-110k5.6 / Q0IIM8* / A3KGB4* / TBC1 domain family member 8B*ENSDARG0000006219216
LO018176.1 / O95759* / TBC1D8* / TBC1 domain family member 8*ENSDARG0000010449314
sgsm3 / Q7T2D0 / small G protein signaling modulator 3 / Q8VCZ6* / Q96HU1*ENSDARG0000001903813
tbc1d30 / TBC1 domain family, member 30 / Q69ZT9* / Q9Y2I9*ENSDARG0000007528111


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationregulation of molecular functionmacromolecule localizationmacromolecule localizationestablishment of localizatioestablishment of localizationcellular localizationcellular localizationcellular component organizatcellular component organizationregulation of molecular funcregulation of molecular function
enzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityenzyme regulator activityprotein bindingprotein binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr