ENSDARG00000063076


Danio rerio

Features
Gene ID: ENSDARG00000063076
  
Biological name :atrip
  
Synonyms : ATR interacting protein / atrip
  
Possible biological names infered from orthology : Q8BMG1 / Q8WXE1
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 10543329
Gene end: 10559760
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000086283
NCBI entrez gene - 558534     See in Manteia.
RefSeq - XM_005173969
RefSeq - NM_001044867
RefSeq - XM_005173968
RefSeq Peptide - NP_001038332
swissprot - Q1LXB1
ZFIN ID - ZDB-GENE-050208-331
Ensembl - ENSDARG00000063076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATRIPENSGALG00000004670Gallus gallus
 ATRIPENSG00000164053Homo sapiens
 AtripENSMUSG00000025646Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR033349  ATR-interacting protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002385 atm / ATM serine/threonine kinase / Q13315* / Q62388* / Serine-protein kinase ATM *  / complex / reaction
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000043480 rbbp8 / F1R983 / retinoblastoma binding protein 8 / Q80YR6* / Q99708* / RB binding protein 8, endonuclease* / retinoblastoma binding protein 8, endonuclease*  / complex / reaction
 ENSDARG00000040303 nbn / nibrin / Q5I2W8 / O60934* / Q9R207*  / complex / reaction
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / reaction
 ENSDARG00000053574 fancd2 / Fanconi anemia, complementation group D2 / Q80V62* / Q9BXW9* / Fanconi anemia group D2 protein homolog *  / complex / reaction
 ENSDARG00000078759 dna2 / DNA replication helicase/nuclease 2 / P51530* / Q6ZQJ5* / DNA replication ATP-dependent helicase/nuclease DNA2 DNA replication nuclease DNA2 DNA replication ATP-dependent helicase DNA2*  / complex / reaction
 ENSDARG00000074410 brip1 / BRCA1 interacting protein C-terminal helicase 1 / Q5SXJ3* / Q9BX63* / Fanconi anemia group J protein homolog *  / complex / reaction
 ENSDARG00000026224 fanci / Fanconi anemia, complementation group I / Q8K368* / Q9NVI1* / Fanconi anemia group I protein homolog *  / complex / reaction
 ENSDARG00000038917 rad50 / RAD50 homolog, double strand break repair protein / Q92878* / AC116366.3* / RAD50 double strand break repair protein*  / complex / reaction
 ENSDARG00000052827 top3a / DNA topoisomerase III alpha / O70157* / Q13472* / topoisomerase (DNA) III alpha*  / complex / reaction
 ENSDARG00000098211 wrn / Werner syndrome / O09053* / Q14191* / Werner syndrome RecQ like helicase*  / complex / reaction
 ENSDARG00000103137 rmi2 / RecQ mediated genome instability 2 / Q3UPE3* / Q96E14* / RecQ-mediated genome instability protein 2 *  / complex / reaction
 ENSDARG00000105014 mre11a / MRE11 homolog A, double strand break repair nuclease / MRE11* / P49959* / MRE11 homolog, double strand break repair nuclease*  / complex / reaction






 

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