ENSDARG00000068086


Danio rerio

Features
Gene ID: ENSDARG00000068086
  
Biological name :psmb11b
  
Synonyms : proteasome subunit beta11b / psmb11b
  
Possible biological names infered from orthology : A5LHX3 / proteasome subunit beta 11 / Proteasome subunit beta type-11 / PSMB11 / Q8BG41
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 1140306
Gene end: 1144425
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089043
NCBI entrez gene - 100331481     See in Manteia.
RefSeq - NM_001281802
RefSeq Peptide - NP_001268731
swissprot - F1QHA5
ZFIN ID - ZDB-GENE-170530-2
Ensembl - ENSDARG00000068086
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A5LHX3ENSG00000222028Homo sapiens
 Psmb11ENSMUSG00000072423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
psmb11a / proteasome subunit beta 11a / A5LHX3* / PSMB11* / proteasome subunit beta 11*ENSDARG0000010853048
psmb5 / proteasome subunit beta 5 / O55234* / P28074* / Proteasome subunit beta type-5 *ENSDARG0000007544529
psmb8a / proteasome subunit beta 8A / PSMB8* / P28063* / P28062* / proteasome subunit beta 8* / Proteasome subunit beta type-8 *ENSDARG0000000130328


Protein motifs (from Interpro)
Interpro ID Name
 IPR001353  Proteasome, subunit alpha/beta
 IPR016050  Proteasome beta-type subunit, conserved site
 IPR023333  Proteasome B-type subunit
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR034385  Proteasome subunit beta type 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005839 proteasome core complex IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004298 threonine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Cross-presentation of soluble exogenous antigens (endosomes)
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
CDT1 association with the CDC6:ORC:origin complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Ubiquitin-dependent degradation of Cyclin D1
G2/M Checkpoints
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of PTEN stability and activity
Neddylation
Interleukin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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