ENSDARG00000108530


Danio rerio

Features
Gene ID: ENSDARG00000108530
  
Biological name :psmb11a
  
Synonyms : proteasome subunit beta 11a / psmb11a
  
Possible biological names infered from orthology : A5LHX3 / proteasome subunit beta 11 / Proteasome subunit beta type-11 / PSMB11 / Q8BG41
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 38370535
Gene end: 38371942
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000151058
NCBI entrez gene - 446135     See in Manteia.
swissprot - B0R027
Ensembl - ENSDARG00000108530
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A5LHX3ENSG00000222028Homo sapiens
 Psmb11ENSMUSG00000072423Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
psmb11b / proteasome subunit beta11b / A5LHX3* / PSMB11* / proteasome subunit beta 11*ENSDARG0000006808646
psmb8a / proteasome subunit beta 8A / PSMB8* / P28063* / P28062* / proteasome subunit beta 8* / Proteasome subunit beta type-8 *ENSDARG0000000130326
psmb5 / proteasome subunit beta 5 / O55234* / P28074* / Proteasome subunit beta type-5 *ENSDARG0000007544524


Protein motifs (from Interpro)
Interpro ID Name
 IPR001353  Proteasome, subunit alpha/beta
 IPR029055  Nucleophile aminohydrolases, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005839 proteasome core complex IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004298 threonine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
FCERI mediated NF-kB activation
The role of GTSE1 in G2/M progression after G2 checkpoint
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Antigen processing: Ubiquitination & Proteasome degradation
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Degradation of GLI1 by the proteasome
Regulation of ornithine decarboxylase (ODC)
Regulation of RAS by GAPs
Asymmetric localization of PCP proteins
Degradation of beta-catenin by the destruction complex
Autodegradation of the E3 ubiquitin ligase COP1
APC/C:Cdc20 mediated degradation of Securin
G2/M Checkpoints
CDT1 association with the CDC6:ORC:origin complex
Dectin-1 mediated noncanonical NF-kB signaling
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Activation of NF-kappaB in B cells
AUF1 (hnRNP D0) binds and destabilizes mRNA
CDK-mediated phosphorylation and removal of Cdc6
CLEC7A (Dectin-1) signaling
Cross-presentation of soluble exogenous antigens (endosomes)
Degradation of AXIN
Degradation of DVL
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Downstream TCR signaling
Interleukin-1 signaling
MAPK6/MAPK4 signaling
Neddylation
NIK-->noncanonical NF-kB signaling
Orc1 removal from chromatin
Regulation of PTEN stability and activity
Separation of Sister Chromatids
TNFR2 non-canonical NF-kB pathway
UCH proteinases
Ub-specific processing proteases
Ubiquitin-dependent degradation of Cyclin D1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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