ENSDARG00000068857


Danio rerio

Features
Gene ID: ENSDARG00000068857
  
Biological name :gbp4
  
Synonyms : gbp4 / guanylate binding protein 4
  
Possible biological names infered from orthology : GBP1 / Gbp10 / Gbp11 / GBP2 / Gbp2b / GBP3 / GBP5 / GBP6 / GBP7 / Gbp8 / Gbp9 / Gm43302 / guanylate binding protein 1 / guanylate binding protein 2 / guanylate binding protein 3 / guanylate binding protein 5 / guanylate binding protein 7 / guanylate binding protein family member 6 / Mus musculus guanylate binding protein 11 (Gbp11), transcript variant 1, mRNA. / Mus musculus guanylate binding protein 3 (Gbp3), transcript variant 4, mRNA. / Mus musculus guanylate binding protein 4 (Gbp4), transcript variant 6, mRNA. / P32455 / P32456 / Q61107 / Q6ZN66 / Q8CFB4 / Q8N8V2 / Q96PP8 / Q96PP9 / Q9H0R5 / Q9Z0E6
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 77681389
Gene end: 77687162
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000090500
NCBI entrez gene - 559296     See in Manteia.
swissprot - Q1MT80
ZFIN ID - ZDB-GENE-060531-46
Ensembl - ENSDARG00000068857
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus
 GBP1ENSG00000117228Homo sapiens
 GBP2ENSG00000162645Homo sapiens
 GBP3ENSG00000117226Homo sapiens
 GBP4ENSG00000162654Homo sapiens
 GBP5ENSG00000154451Homo sapiens
 GBP6ENSG00000183347Homo sapiens
 GBP7ENSG00000213512Homo sapiens
 Gbp10ENSMUSG00000105096Mus musculus
 Gbp11ENSMUSG00000092021Mus musculus
 Gbp2ENSMUSG00000028270Mus musculus
 Gbp2bENSMUSG00000040264Mus musculus
 Gbp3ENSMUSG00000028268Mus musculus
 Gbp4ENSMUSG00000079363Mus musculus
 Gbp5ENSMUSG00000105504Mus musculus
 Gbp6ENSMUSG00000104713Mus musculus
 Gbp7ENSMUSG00000040253Mus musculus
 Gbp8ENSMUSG00000034438Mus musculus
 Gbp9ENSMUSG00000029298Mus musculus
 Gm43302ENSMUSG00000079362Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-209n20.1 / Gbp8* / Gbp9* / GBP1* / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / Gbp10* / Gbp11* / Gbp2b* / P32455* / Q9Z0E6* / Q9H0R5* / Q96PP9* / Q96PP8* / Q8N8V2* / Q8CFB4* / ...ENSDARG0000009938260
si:dkeyp-30d6.2 / Gbp8* / Gbp9* / GBP1* / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / Gbp10* / Gbp11* / Gbp2b* / P32455* / Q9Z0E6* / Q9H0R5* / Q96PP9* / Q96PP8* / Q8N8V2* / Q8CFB4* / Q6...ENSDARG0000010356451
gbp1 / guanylate binding protein 1 / Gbp8* / Gbp9* / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / Gbp10* / Gbp2b* / Gbp11* / Q9Z0E6* / P32455* / P32456* / Q61107* / Q6ZN66* / Q8CFB4* / Q...ENSDARG0000003866842
gbp2 / guanylate binding protein 2 / GBP1* / GBP7* / Gbp8* / Gbp9* / GBP3* / GBP4* / GBP5* / GBP6* / Gbp10* / Gbp2b* / Gbp11* / Q9Z0E6* / P32455* / P32456* / Q61107* / Q6ZN66* / Q8CFB4* / Q...ENSDARG0000003866936
unm_sa911 / un-named sa911 / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / GBP2* / GBP1* / Q6ZN66* / Q8N8V2* / Q96PP8* / Q96PP9* / Q9H0R5* / P32455* / P32456* / guanylate binding protein 2* / gua...ENSDARG0000003406329
CABZ01068208.1 / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / GBP1* / Q9H0R5* / P32455* / P32456* / Q6ZN66* / Q8N8V2* / Q96PP8* / Q96PP9* / guanylate binding protein 1* / guanylate bindi...ENSDARG0000011267519
zmp:0000000527 / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / GBP1* / P32456* / Q6ZN66* / Q8N8V2* / Q96PP8* / Q96PP9* / Q9H0R5* / P32455* / guanylate binding protein 1* / guanylate bindi...ENSDARG0000000562718
CABZ01068209.1 / GBP2* / GBP3* / GBP4* / GBP5* / GBP6* / GBP7* / GBP1* / Q9H0R5* / P32455* / P32456* / Q6ZN66* / Q8N8V2* / Q96PP8* / Q96PP9* / guanylate binding protein 1* / guanylate bindi...ENSDARG0000011061610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR011029  Death-like domain superfamily
 IPR015894  Guanylate-binding protein, N-terminal
 IPR025307  FIIND domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR033516  CARD8/ASC/NALP1, CARD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001780 neutrophil homeostasis IMP
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0042742 defense response to bacterium IMP
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0070944 neutrophil mediated killing of bacterium IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , ameliorated
whole organism decreased life span , exacerbated
Show

 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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