ENSMUSG00000079363


Mus musculus

Features
Gene ID: ENSMUSG00000079363
  
Biological name :Gbp4
  
Synonyms : Gbp4 / Mus musculus guanylate binding protein 4 (Gbp4), transcript variant 6, mRNA.
  
Possible biological names infered from orthology : GBP6 / guanylate binding protein family member 6 / Q6ZN66
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E5
Gene start: 105115767
Gene end: 105139586
  
Corresponding Affymetrix probe sets: 10531987 (MoGene1.0st)   10531994 (MoGene1.0st)   1421104_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143689
Ensembl peptide - ENSMUSP00000142528
Ensembl peptide - ENSMUSP00000098522
Ensembl peptide - ENSMUSP00000142493
Ensembl peptide - ENSMUSP00000142795
NCBI entrez gene - 17472     See in Manteia.
MGI - MGI:97072
RefSeq - XM_017320702
RefSeq - NM_001359079
RefSeq - NM_001359080
RefSeq - NM_001359081
RefSeq - NM_001359082
RefSeq - NM_008620
RefSeq - XM_006534803
RefSeq - XM_006534804
RefSeq - XM_006534805
RefSeq - XM_006534806
RefSeq - XM_006534807
RefSeq - XM_011249411
RefSeq - NM_001256005
RefSeq Peptide - NP_001242934
RefSeq Peptide - NP_001346008
RefSeq Peptide - NP_001346009
RefSeq Peptide - NP_001346010
RefSeq Peptide - NP_001346011
RefSeq Peptide - NP_032646
swissprot - A4UUI3
swissprot - A0A0G2JGT4
swissprot - A0A0G2JEJ5
swissprot - A4UUI4
swissprot - A0A0G2JDT5
Ensembl - ENSMUSG00000079363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068208.1ENSDARG00000112675Danio rerio
 CABZ01068209.1ENSDARG00000110616Danio rerio
 gbp1ENSDARG00000038668Danio rerio
 gbp2ENSDARG00000038669Danio rerio
 gbp4ENSDARG00000068857Danio rerio
 si:ch211-209n20.1ENSDARG00000099382Danio rerio
 si:dkeyp-30d6.2ENSDARG00000103564Danio rerio
 unm_sa911ENSDARG00000034063Danio rerio
 zmp:0000000527ENSDARG00000005627Danio rerio
 ENSGALG00000000720Gallus gallus
 GBPENSGALG00000026152Gallus gallus
 GBP6ENSG00000183347Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gbp9 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000002929877
Gm43302 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000007936277
Gbp6 / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000010471377
Gbp10 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000010509677
Gbp8 / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000003443868
Gbp7 / GBP4* / Q8N8V2* / Q96PP9* / guanylate binding protein 4* / guanylate binding protein 7*ENSMUSG0000004025360
Gbp11 / Mus musculus guanylate binding protein 11 (Gbp11), transcript variant 1, mRNA. / GBP6* / Q6ZN66* / guanylate binding protein family member 6*ENSMUSG0000009202160
Gbp3 / Q61107 / Mus musculus guanylate binding protein 3 (Gbp3), transcript variant 4, mRNA. / GBP4* / GBP7* / Q96PP9* / Q8N8V2* / guanylate binding protein 4* / guanylate binding protein 7*ENSMUSG0000002826858
Gbp2 / Q9Z0E6 / Guanylate-binding protein 2 / P32456*ENSMUSG0000002827044
Gbp2b / GBP2* / P32456* / guanylate binding protein 2*ENSMUSG0000004026442
Gbp5 / Q8CFB4 / Guanylate-binding protein 5 / Q96PP8*ENSMUSG0000010550439


Protein motifs (from Interpro)
Interpro ID Name
 IPR003191  Guanylate-binding protein/Atlastin, C-terminal
 IPR015894  Guanylate-binding protein, N-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030386  GB1/RHD3-type guanine nucleotide-binding (G) domain
 IPR036543  Guanylate-binding protein, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0001933 negative regulation of protein phosphorylation IDA
 biological_processGO:0031397 negative regulation of protein ubiquitination IGI
 biological_processGO:0032687 negative regulation of interferon-alpha production IMP
 biological_processGO:0042308 negative regulation of protein import into nucleus IDA
 biological_processGO:0050688 regulation of defense response to virus IMP
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr