ENSDARG00000078717


Danio rerio

Features
Gene ID: ENSDARG00000078717
  
Biological name :itga8
  
Synonyms : integrin, alpha 8 / itga8
  
Possible biological names infered from orthology : A2ARA8 / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain / integrin subunit alpha 8 / P53708
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 28383758
Gene end: 28512860
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000059037
Ensembl peptide - ENSDARP00000118449
NCBI entrez gene - 100141346     See in Manteia.
swissprot - E7F7L7
swissprot - E9QIZ0
ZFIN ID - ZDB-GENE-080220-48
Ensembl - ENSDARG00000078717
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITGA8ENSGALG00000008747Gallus gallus
 ITGA8ENSG00000077943Homo sapiens
 Itga8ENSMUSG00000026768Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itga5 / integrin, alpha 5 (fibronectin receptor, alpha polypeptide) / P08648* / P11688* / integrin subunit alpha 5* / Integrin alpha-5 Integrin alpha-5 heavy chain Integrin alpha-5 light chain*ENSDARG0000000635347
itgav / integrin, alpha V / P06756* / integrin subunit alpha V*ENSDARG0000000631446
itga2b / integrin, alpha 2b / P08514* / Q9QUM0* / integrin subunit alpha 2b*ENSDARG0000001868740
itga6b / integrin, alpha 6b / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000006994626
itga3b / integrin, alpha 3b / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000001282425
itga6a / integrin, alpha 6a / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000004228225
itga6l / integrin, alpha 6, like / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000005601825
itga9 / integrin, alpha 9 / Q13797* / integrin subunit alpha 9*ENSDARG0000003243524
itga4 / integrin alpha 4 / P13612* / integrin subunit alpha 4*ENSDARG0000010305624
itga3a / integrin, alpha 3a / ITGA3* / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSDARG0000003791723
itga11b / integrin, alpha 11b / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000000795022
itga11a / integrin, alpha 11a / ITGA11* / Q9UKX5* / integrin subunit alpha 11*ENSDARG0000003608622
itga1 / integrin, alpha 1 / P56199* / Q3V3R4* / integrin subunit alpha 1*ENSDARG0000007431622
itga10 / integrin, alpha 10 / O75578* / integrin subunit alpha 10*ENSDARG0000000250721
itga2.2 / integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2 / ITGA2* / P17301* / Q62469* / Integrin alpha-2 * / integrin subunit alpha 2*ENSDARG0000006297420
si:dkey-32n7.4 / ITGAD* / ITGAM* / ITGAX* / Q13349* / P11215* / P20702* / Q9QXH4* / Q3V0T4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integ...ENSDARG0000000295618
zmp:0000001082 / ITGAL* / P20701* / P24063* / Integrin alpha-L * / integrin subunit alpha L*ENSDARG0000009889917
itgae.2 / integrin, alpha E, tandem duplicate 2 / ITGAE* / P38570* / Q60677* / integrin subunit alpha E* / integrin alpha E, epithelial-associated*ENSDARG0000005778714
itgam / integrin, alpha M (complement component 3 receptor 3 subunit) / ITGAD* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin...ENSDARG0000009658714
CU469503.1 / ITGA6* / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSDARG0000009934810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres
Integrin cell surface interactions
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000692 symplectic symplectic length , abnormal
symplectic decreased length , abnormal
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 ZFA:0001058 caudal fin caudal fin blistered , abnormal
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 ZFA:0001094 whole organism whole organism decreased amount , abnormal
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 ZFA:0001104 pharyngeal endoderm pharyngeal endoderm increased distance pharyngeal ectoderm , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage fused with palatoquadrate cartilage , abnormal
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 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage fused with ceratohyal cartilage , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell intraciliary transport decreased process quality , abnormal
neuromast hair cell kinocilium absent , abnormal
neuromast hair cell kinocilium decreased amount , abnormal
neuromast hair cell kinociliary basal body spatial pattern , abnormal
neuromast hair cell endocytosis decreased process quality , abnormal
neuromast hair cell kinocilium decreased length , abnormal
neuromast hair cell cilium assembly decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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