ENSGALG00000008747


Gallus gallus

Features
Gene ID: ENSGALG00000008747
  
Biological name :ITGA8
  
Synonyms : integrin alpha-8 precursor / ITGA8
  
Possible biological names infered from orthology : A2ARA8 / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain / integrin subunit alpha 8 / P53708
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 20364201
Gene end: 20463104
  
Corresponding Affymetrix probe sets: Gga.1784.1.S1_at (Chicken Array)   Gga.1784.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053893
Ensembl peptide - ENSGALP00000014220
NCBI entrez gene - 396225     See in Manteia.
RefSeq - XM_015281312
RefSeq - NM_205288
RefSeq - XM_015281310
RefSeq - XM_015281311
RefSeq Peptide - NP_990619
swissprot - F1NSA4
swissprot - A0A1D5PM20
Ensembl - ENSGALG00000008747
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga8ENSDARG00000078717Danio rerio
 ITGA8ENSG00000077943Homo sapiens
 Itga8ENSMUSG00000026768Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGAV / integrin alpha-V precursor / P06756* / P43406* / integrin subunit alpha V* / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain*ENSGALG0000000265546
ITGA3 / integrin alpha-3 precursor / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSGALG0000003270227
ITGA6 / integrin alpha-6 precursor / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSGALG0000003400727
ITGA9 / integrin alpha-9 precursor / B8JK39* / Q13797* / Integrin alpha-9 * / integrin subunit alpha 9*ENSGALG0000002937824
ITGA4 / integrin subunit alpha 4 / P13612*ENSGALG0000004157723
ITGA11 / integrin subunit alpha 11 / Q9UKX5*ENSGALG0000000800722
ITGA2 / integrin subunit alpha 2 / P17301* / Q62469* / Integrin alpha-2 *ENSGALG0000001490322
ITGA1 / integrin alpha-1 precursor / Q3V3R4* / P56199* / Integrin alpha-1 * / integrin subunit alpha 1*ENSGALG0000001489121
ITGAD* / ITGAM* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integrin subunit alpha...ENSGALG0000004129817


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030198 extracellular matrix organization IEA
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0048333 mesodermal cell differentiation IEA
 biological_processGO:0048745 smooth muscle tissue development IEA
 biological_processGO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045177 apical part of cell IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres
Integrin cell surface interactions
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex
 ENSGALG00000039990 TNC / tenascin C / P24821* / Q80YX1*  / complex / reaction






 

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