ENSGALG00000014891


Gallus gallus

Features
Gene ID: ENSGALG00000014891
  
Biological name :ITGA1
  
Synonyms : integrin alpha-1 precursor / ITGA1
  
Possible biological names infered from orthology : Integrin alpha-1 / integrin subunit alpha 1 / P56199 / Q3V3R4
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 15771740
Gene end: 15844439
  
Corresponding Affymetrix probe sets: Gga.16495.1.S1_at (Chicken Array)   Gga.566.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000032219
Ensembl peptide - ENSGALP00000023976
NCBI entrez gene - 395951     See in Manteia.
RefSeq - NM_205069
RefSeq Peptide - NP_990400
swissprot - F1N8Z0
swissprot - E1C0V6
Ensembl - ENSGALG00000014891
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga1ENSDARG00000074316Danio rerio
 ITGA1ENSG00000213949Homo sapiens
 Itga1ENSMUSG00000042284Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA11 / integrin subunit alpha 11 / Q9UKX5*ENSGALG0000000800739
ITGA2 / integrin subunit alpha 2 / P17301* / Q62469* / Integrin alpha-2 *ENSGALG0000001490339
ITGAD* / ITGAM* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integrin subunit alpha...ENSGALG0000004129822
ITGA8 / integrin alpha-8 precursor / A2ARA8* / P53708* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*ENSGALG0000000874719
ITGA9 / integrin alpha-9 precursor / B8JK39* / Q13797* / Integrin alpha-9 * / integrin subunit alpha 9*ENSGALG0000002937819
ITGAV / integrin alpha-V precursor / P06756* / P43406* / integrin subunit alpha V* / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain*ENSGALG0000000265518
ITGA3 / integrin alpha-3 precursor / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSGALG0000003270218
ITGA4 / integrin subunit alpha 4 / P13612*ENSGALG0000004157718
ITGA6 / integrin alpha-6 precursor / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSGALG0000003400717


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0030593 neutrophil chemotaxis IEA
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0045123 cellular extravasation IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034665 integrin alpha1-beta1 complex IEA
 cellular_componentGO:0045178 basal part of cell IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0098639 collagen binding involved in cell-matrix adhesion IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex






 

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