ENSGALG00000014903


Gallus gallus

Features
Gene ID: ENSGALG00000014903
  
Biological name :ITGA2
  
Synonyms : integrin subunit alpha 2 / ITGA2
  
Possible biological names infered from orthology : Integrin alpha-2 / P17301 / Q62469
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 15862498
Gene end: 15924378
  
Corresponding Affymetrix probe sets: GgaAffx.9457.1.S1_at (Chicken Array)   GgaAffx.9461.1.S1_at (Chicken Array)   GgaAffx.9463.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052182
Ensembl peptide - ENSGALP00000023991
NCBI entrez gene - 100857227     See in Manteia.
RefSeq - XM_015277561
RefSeq - XM_003642982
swissprot - F1N8T2
swissprot - A0A1D5PHA5
Ensembl - ENSGALG00000014903
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itga2.2ENSDARG00000062974Danio rerio
 ITGA2ENSG00000164171Homo sapiens
 Itga2ENSMUSG00000015533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGA1 / integrin alpha-1 precursor / Q3V3R4* / P56199* / Integrin alpha-1 * / integrin subunit alpha 1*ENSGALG0000001489138
ITGA11 / integrin subunit alpha 11 / Q9UKX5*ENSGALG0000000800737
ITGAD* / ITGAM* / ITGAX* / P11215* / P20702* / Q13349* / Q3V0T4* / Q9QXH4* / integrin alpha M* / Integrin alpha-X * / Integrin alpha-D * / integrin subunit alpha X* / integrin subunit alpha...ENSGALG0000004129821
ITGAV / integrin alpha-V precursor / P06756* / P43406* / integrin subunit alpha V* / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain*ENSGALG0000000265520
ITGA8 / integrin alpha-8 precursor / A2ARA8* / P53708* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*ENSGALG0000000874720
ITGA9 / integrin alpha-9 precursor / B8JK39* / Q13797* / Integrin alpha-9 * / integrin subunit alpha 9*ENSGALG0000002937819
ITGA6 / integrin alpha-6 precursor / P23229* / Q61739* / integrin subunit alpha 6* / Integrin alpha-6 Integrin alpha-6 heavy chain Integrin alpha-6 light chain*ENSGALG0000003400719
ITGA3 / integrin alpha-3 precursor / P26006* / Q62470* / integrin subunit alpha 3* / Integrin alpha-3 Integrin alpha-3 heavy chain Integrin alpha-3 light chain*ENSGALG0000003270218
ITGA4 / integrin subunit alpha 4 / P13612*ENSGALG0000004157718


Protein motifs (from Interpro)
Interpro ID Name
 IPR000413  Integrin alpha chain
 IPR002035  von Willebrand factor, type A
 IPR013517  FG-GAP repeat
 IPR013519  Integrin alpha beta-propellor
 IPR013649  Integrin alpha-2
 IPR018184  Integrin alpha chain, C-terminal cytoplasmic region, conserved site
 IPR032695  Integrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006929 substrate-dependent cell migration IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0033627 cell adhesion mediated by integrin IEA
 biological_processGO:0038065 collagen-activated signaling pathway IEA
 biological_processGO:0048333 mesodermal cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034666 integrin alpha2-beta1 complex IEA
 cellular_componentGO:0045178 basal part of cell IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0038064 collagen receptor activity IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0098639 collagen binding involved in cell-matrix adhesion IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
MET activates PTK2 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex
 ENSGALG00000011271 LUM / P51890 / Lumican / P51884* / P51885*  / complex / reaction






 

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