ENSGALG00000011271


Gallus gallus

Features
Gene ID: ENSGALG00000011271
  
Biological name :LUM
  
Synonyms : LUM / Lumican / P51890
  
Possible biological names infered from orthology : P51884 / P51885
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 43987396
Gene end: 43999595
  
Corresponding Affymetrix probe sets: Gga.4078.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062605
Ensembl peptide - ENSGALP00000018370
NCBI entrez gene - 417891     See in Manteia.
RefSeq - NM_001276357
RefSeq Peptide - NP_001263286
swissprot - P51890
swissprot - A0A1L1RUV8
Ensembl - ENSGALG00000011271
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lumENSDARG00000045580Danio rerio
 LUMENSG00000139329Homo sapiens
 LumENSMUSG00000036446Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FMOD / fibromodulin precursor / P50608* / Q06828* / fibromodulin*ENSGALG0000003406745
KERA / O42235 / Keratocan / O35367* / O60938*ENSGALG0000001127038
PRELP / proline and arginine rich end leucine rich repeat protein / P51888* / Q9JK53* / proline arginine-rich end leucine-rich repeat*ENSGALG0000003445637
OMD / osteomodulin / O35103* / Q99983*ENSGALG0000002608036
ASPN / asporin / Q99MQ4* / Q9BXN1*ENSGALG0000000472229
DCN / decorin precursor / P07585* / P28654* / decorin*ENSGALG0000001127429
ECM2 / extracellular matrix protein 2 / O94769* / Q5FW85*ENSGALG0000000469527
PODN / podocan / Q7TQ62* / Q7Z5L7*ENSGALG0000002186927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR027219  Lumican
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0030199 collagen fibril organization IEA
 biological_processGO:0032914 positive regulation of transforming growth factor beta1 production IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005583 fibrillar collagen trimer IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005518 collagen binding IEA


Pathways (from Reactome)
Pathway description
Keratan sulfate biosynthesis
Keratan sulfate degradation
Integrin cell surface interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex / reaction
 ENSGALG00000014903 ITGA2 / integrin subunit alpha 2 / P17301* / Q62469* / Integrin alpha-2 *  / complex / reaction






 

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