ENSGALG00000039990


Gallus gallus

Features
Gene ID: ENSGALG00000039990
  
Biological name :TNC
  
Synonyms : tenascin C / TNC
  
Possible biological names infered from orthology : P24821 / Q80YX1
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 3145480
Gene end: 3214636
  
Corresponding Affymetrix probe sets: Gga.3818.1.S1_at (Chicken Array)   Gga.404.1.A1_at (Chicken Array)   Gga.404.1.S1_at (Chicken Array)   Gga.684.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045950
Ensembl peptide - ENSGALP00000058289
Ensembl peptide - ENSGALP00000055849
Ensembl peptide - ENSGALP00000052880
NCBI entrez gene - 396440     See in Manteia.
RefSeq - XM_015279340
RefSeq - XM_015279345
RefSeq - XM_015279344
RefSeq - XM_015279342
RefSeq - NM_205456
RefSeq - XM_015279341
RefSeq Peptide - NP_990787
swissprot - A0A1D5PZ80
swissprot - A0A1D5NZY0
swissprot - A0A1D5PJ88
swissprot - A0A1D5PSG3
Ensembl - ENSGALG00000039990
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tncENSDARG00000021948Danio rerio
 zmp:0000000846ENSDARG00000078362Danio rerio
 TNCENSG00000041982Homo sapiens
 TncENSMUSG00000028364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNR / tenascin-R precursor / Q8BYI9* / Q92752* / tenascin R*ENSGALG0000000452628
FN1 / fibronectin 1 / P02751* / P11276* / Fibronectin Anastellin*ENSGALG0000000357819
TNN / tenascin N / Q80Z71* / Q9UQP3*ENSGALG0000000453819
TNXB* / P22105* / tenascin XB*ENSGALG0000004103115
FGA / fibrinogen alpha chain isoform 1 precursor / E9PV24* / P02671* / fibrinogen alpha chain* / Fibrinogen alpha chain Fibrinopeptide A Fibrinogen alpha chain*ENSGALG000000092666
ANGPTL4 / angiopoietin like 4 / Q9BY76* / Q9Z1P8* / Angiopoietin-related protein 4 *ENSGALG000000006195
FGB / fibrinogen beta chain / P02675* / Q8K0E8* / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain*ENSGALG000000092625
FGG / fibrinogen gamma chain / P02679* / Q8VCM7*ENSGALG000000092685
FGL1 / fibrinogen like 1 / Q08830*ENSGALG000000136065
ANGPTL3 / angiopoietin-related protein 3 precursor / Q9R182* / Q9Y5C1* / angiopoietin like 3* / Angiopoietin-related protein 3 ANGPTL3(17-224)*ENSGALG000000109784
ENSGALG000000170294
ANGPTL5 / Q86XS5* / angiopoietin like 5*ENSGALG000000171914
ENSGALG000000333144
ANGPT1L / angiopoietin-related protein 1-like precursor ENSGALG000000415024
ENSGALG000000418334
ENSGALG000000428194
ENSGALG000000452384
ENSGALG000000464824
ENSGALG000000275203


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR003961  Fibronectin type III
 IPR013032  EGF-like, conserved site
 IPR013111  EGF-like domain, extracellular
 IPR013783  Immunoglobulin-like fold
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR033078  Tenascin-C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014012 peripheral nervous system axon regeneration IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development IEA
 biological_processGO:0060740 prostate gland epithelium morphogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005614 interstitial matrix IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0045545 syndecan binding IEA


Pathways (from Reactome)
Pathway description
Integrin cell surface interactions
ECM proteoglycans
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000379 ITGB3 / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*  / complex / reaction
 ENSGALG00000003578 FN1 / fibronectin 1 / P02751* / P11276* / Fibronectin Anastellin*  / complex / reaction
 ENSGALG00000007145 ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *  / complex / reaction
 ENSGALG00000008747 ITGA8 / integrin alpha-8 precursor / A2ARA8* / P53708* / integrin subunit alpha 8* / Integrin alpha-8 Integrin alpha-8 heavy chain Integrin alpha-8 light chain*  / complex / reaction
 ENSGALG00000039990 TNC / tenascin C / P24821* / Q80YX1*  / complex






 

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