ENSDARG00000086057


Danio rerio

Features
Gene ID: ENSDARG00000086057
  
Biological name :plxnd1
  
Synonyms : plexin D1 / plxnd1
  
Possible biological names infered from orthology : Q3UH93 / Q9Y4D7
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 54284961
Gene end: 54286201
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112069
swissprot - E7FGF3
ZFIN ID - ZDB-GENE-040426-1828
Ensembl - ENSDARG00000086057
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLXND1ENSGALG00000008473Gallus gallus
 PLXND1ENSG00000004399Homo sapiens
 Plxnd1ENSMUSG00000030123Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plxnb1b / plexin b1b / O43157* / PLXNB1* / plexin B1*ENSDARG0000001721125
plxnb3 / plexin B3 / Q9QY40* / Q9ULL4*ENSDARG0000003299025
plxnb1a / plexin b1a / PLXNB1* / O43157* / Q8CJH3* / plexin B1*ENSDARG0000007582124
plxna4 / plexin A4 / Q80UG2* / Q9HCM2*ENSDARG0000001932822
plxnb2a / plexin b2a / O15031* / B2RXS4* / PLXNB2* / plexin B2*ENSDARG0000000381121
plxnb2b / plexin b2b / O15031* / PLXNB2* / plexin B2*ENSDARG0000003698521
plxna1a / plexin A1a / PLXNA1* / Q9UIW2* / plexin A1*ENSDARG0000010545221
plxna2 / plexin A2 / O75051* / P70207*ENSDARG0000006037220
si:dkey-183c2.4 / B2RXS4* / O15031* / PLXNB2* / plexin B2*ENSDARG0000007989220
plxnb2a / plexin b2a / O15031* / B2RXS4* / PLXNB2* / plexin B2*ENSDARG0000009479920
LO018148.1 / PLXNA1* / Q9UIW2* / plexin A1*ENSDARG0000011482320
plxna3 / plexin A3 / P51805* / P70208*ENSDARG0000000717219
si:ch211-127b11.1 / B2RXS4* / O15031* / PLXNB2* / plexin B2*ENSDARG0000007709012
plxnc1 / plexin C1 / O60486* / Q9QZC2*ENSDARG000000152780


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR031148  Plexin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001763 morphogenesis of a branching structure IMP
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0007162 negative regulation of cell adhesion IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0035476 angioblast cell migration IMP
 biological_processGO:0043087 regulation of GTPase activity IBA
 biological_processGO:0048048 embryonic eye morphogenesis IMP
 biological_processGO:0050772 positive regulation of axonogenesis IBA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0017154 semaphorin receptor activity IEA


Pathways (from Reactome)
Pathway description
Other semaphorin interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000180 caudal vein caudal vein morphology , abnormal
Show

 ZFA:0000186 common cardinal vein common cardinal vein increased width , abnormal
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 ZFA:0001061 intersegmental artery intersegmental artery increased branchiness , abnormal
intersegmental artery angiogenic sprout increased amount , abnormal
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 ZFA:0001073 axial vasculature axial vasculature has extra parts of type intersegmental vessel , abnormal
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 ZFA:0001079 blood vasculature blood vasculature quality , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
intersegmental vessel spatial pattern , abnormal
intersegmental vessel increased branchiness , abnormal
intersegmental vessel mislocalised , abnormal
intersegmental vessel position , abnormal
intersegmental vessel disorganized , abnormal
intersegmental vessel shape , abnormal
intersegmental vessel irregular spatial pattern , abnormal
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 ZFA:0005046 hyaloid vessel hyaloid vessel irregular spatial pattern , abnormal
hyaloid vessel hypoplastic , abnormal
hyaloid vessel branchiness , abnormal
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 ZFA:0005559 vascular sprouts vascular sprouts mislocalised , abnormal
vascular sprouts disorganized , abnormal
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 ZFA:0005604 angiogenic sprout angiogenic sprout increased amount , abnormal
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 ZFA:0005759 visceral fat visceral fat decreased volume , abnormal
visceral fat lipid droplet morphology , abnormal
visceral fat lipid droplet increased amount , abnormal
visceral fat cell proliferation increased process quality , abnormal
visceral fat collagen fibril organization process quality , abnormal
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 ZFA:0007057 ocular blood vessel ocular blood vessel structure , abnormal
ocular blood vessel increased amount , abnormal
ocular blood vessel kinked , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell increased amount , abnormal
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 ZFA:0009082 fat cell fat cell cell proliferation increased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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