ENSDARG00000019328


Danio rerio

Features
Gene ID: ENSDARG00000019328
  
Biological name :plxna4
  
Synonyms : plexin A4 / plxna4
  
Possible biological names infered from orthology : Q80UG2 / Q9HCM2
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 15217929
Gene end: 15420452
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000021195
NCBI entrez gene - 325938     See in Manteia.
RefSeq - XM_005164690
swissprot - T1ECS6
ZFIN ID - ZDB-GENE-030131-4663
Ensembl - ENSDARG00000019328
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLXNA4ENSGALG00000006473Gallus gallus
 PLXNA4ENSG00000221866Homo sapiens
 Plxna4ENSMUSG00000029765Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plxna2 / plexin A2 / O75051* / P70207*ENSDARG0000006037267
plxna1a / plexin A1a / PLXNA1* / Q9UIW2* / plexin A1*ENSDARG0000010545262
plxna3 / plexin A3 / P51805* / P70208*ENSDARG0000000717260
LO018148.1 / PLXNA1* / Q9UIW2* / plexin A1*ENSDARG0000011482356
plxnb1b / plexin b1b / O43157* / PLXNB1* / plexin B1*ENSDARG0000001721135
plxnb3 / plexin B3 / Q9QY40* / Q9ULL4*ENSDARG0000003299034
plxnb2a / plexin b2a / O15031* / B2RXS4* / PLXNB2* / plexin B2*ENSDARG0000000381131
plxnb2b / plexin b2b / O15031* / PLXNB2* / plexin B2*ENSDARG0000003698531
plxnb1a / plexin b1a / PLXNB1* / O43157* / Q8CJH3* / plexin B1*ENSDARG0000007582129
plxnc1 / plexin C1 / O60486* / Q9QZC2*ENSDARG0000001527816
si:dkey-183c2.4 / B2RXS4* / O15031* / PLXNB2* / plexin B2*ENSDARG000000798928
plxnb2a / plexin b2a / O15031* / B2RXS4* / PLXNB2* / plexin B2*ENSDARG000000947998
si:ch211-127b11.1 / B2RXS4* / O15031* / PLXNB2* / plexin B2*ENSDARG000000770906
plxnd1 / plexin D1 / Q3UH93* / Q9Y4D7*ENSDARG000000860575


Protein motifs (from Interpro)
Interpro ID Name
 IPR001627  Sema domain
 IPR002165  Plexin repeat
 IPR002909  IPT domain
 IPR008936  Rho GTPase activation protein
 IPR013548  Plexin, cytoplasmic RasGAP domain
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016201  PSI domain
 IPR031148  Plexin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0017154 semaphorin receptor activity IEA


Pathways (from Reactome)
Pathway description
Sema3A PAK dependent Axon repulsion
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
CRMPs in Sema3A signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000017803 gsk3b / glycogen synthase kinase 3 beta / P49841* / Q9WV60*  / reaction
 ENSDARG00000002587 dpysl3 / Q52PJ5 / dihydropyrimidinase-like 3 / Q14195*  / reaction / complex
 ENSDARG00000016429 farp2 / FERM, RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARH/RhoGEF and pleckstrin domain protein 2* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *  / complex
 ENSDARG00000102153 nrp1a / neuropilin 1a / NRP1* / O14786* / P97333* / neuropilin 1*  / complex
 ENSDARG00000103490 dpysl4 / dihydropyrimidinase-like 4 / O14531*  / reaction / complex
 ENSDARG00000025319 fynb / F1RDG9 / FYN proto-oncogene, Src family tyrosine kinase b / FYN* / P39688* / P06241* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSDARG00000045087 cdk5r1b / cyclin-dependent kinase 5, regulatory subunit 1b (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / complex
 ENSDARG00000056683 cdk5 / cyclin-dependent kinase 5 / P49615* / Q00535* / Cyclin-dependent-like kinase 5 *  / complex
 ENSDARG00000052468 si:dkeyp-80c12.7 / GSK3B (1 of many) / GSK3B* / P49841* / Q9WV60* / glycogen synthase kinase 3 beta*  / reaction
 ENSDARG00000037916 cdk5r1a / cyclin-dependent kinase 5, regulatory subunit 1a (p35) / Q15078* / P61809* / CDK5R1* / cyclin dependent kinase 5 regulatory subunit 1* / Cyclin-dependent kinase 5 activator 1 Cycl...  / complex
 ENSDARG00000011370 fyna / Q6EWH2 / FYN proto-oncogene, Src family tyrosine kinase a / FYN* / P06241* / P39688* / Tyrosine-protein kinase Fyn * / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSDARG00000011449 fes / FES proto-oncogene, tyrosine kinase / P07332* / P16879* / Tyrosine-protein kinase Fes/Fps *  / complex






 

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