ENSDARG00000087574


Danio rerio

Features
Gene ID: ENSDARG00000087574
  
Biological name :nox1
  
Synonyms : NADPH oxidase 1 / nox1
  
Possible biological names infered from orthology : Q8CIZ9 / Q9Y5S8
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 41345175
Gene end: 41361847
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000080539
NCBI entrez gene - 555604     See in Manteia.
RefSeq - XM_009291119
swissprot - F6NMX7
ZFIN ID - ZDB-GENE-070404-1
Ensembl - ENSDARG00000087574
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NOX1ENSGALG00000006707Gallus gallus
 NOX1ENSG00000007952Homo sapiens
 Nox1ENSMUSG00000031257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cybb / cytochrome b-245, beta polypeptide (chronic granulomatous disease) / Q61093* / P04839* / cytochrome b-245 beta chain* / Cytochrome b-245 heavy chain *ENSDARG0000005661560
duox / dual oxidase / DUOX1* / DUOX2* / Q9NRD9* / Q9NRD8* / dual oxidase 1* / dual oxidase 2*ENSDARG0000006263229
nox5 / NADPH oxidase, EF-hand calcium binding domain 5 / Q96PH1* / NADPH oxidase 5*ENSDARG0000007977329
NOX4 / NADPH oxidase 4 / Q9NPH5*ENSDARG0000011493715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000778  Cytochrome b245, heavy chain
 IPR013112  FAD-binding 8
 IPR013121  Ferric reductase, NAD binding domain
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042554 superoxide anion generation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016175 superoxide-generating NADPH oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate NADPH Oxidases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism reactive oxygen species decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018283 cyba / cytochrome b-245, alpha polypeptide / P13498* / cytochrome b-245 alpha chain*  / complex
 ENSDARG00000056374 noxo1b / NADPH oxidase organizer 1b / NOXO1* / Q8NFA2* / Q8VCM2* / NADPH oxidase organizer 1*  / complex






 

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