ENSDARG00000062632


Danio rerio

Features
Gene ID: ENSDARG00000062632
  
Biological name :duox
  
Synonyms : dual oxidase / duox
  
Possible biological names infered from orthology : dual oxidase 1 / dual oxidase 2 / DUOX1 / DUOX2 / Q9NRD8 / Q9NRD9
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 31958911
Gene end: 32018990
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000085160
Ensembl peptide - ENSDARP00000148299
Ensembl peptide - ENSDARP00000155366
swissprot - F1QVF2
ZFIN ID - ZDB-GENE-091117-14
Ensembl - ENSDARG00000062632
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000041510Gallus gallus
 DUOX1ENSG00000137857Homo sapiens
 DUOX2ENSG00000140279Homo sapiens
 Duox1ENSMUSG00000033268Mus musculus
 Duox2ENSMUSG00000068452Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nox5 / NADPH oxidase, EF-hand calcium binding domain 5 / Q96PH1* / NADPH oxidase 5*ENSDARG0000007977312
nox1 / NADPH oxidase 1 / Q8CIZ9* / Q9Y5S8*ENSDARG0000008757411
cybb / cytochrome b-245, beta polypeptide (chronic granulomatous disease) / Q61093* / P04839* / cytochrome b-245 beta chain* / Cytochrome b-245 heavy chain *ENSDARG0000005661510
NOX4 / NADPH oxidase 4 / Q9NPH5*ENSDARG000001149374


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR010255  Haem peroxidase
 IPR011992  EF-hand domain pair
 IPR013112  FAD-binding 8
 IPR013121  Ferric reductase, NAD binding domain
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel
 IPR018247  EF-Hand 1, calcium-binding site
 IPR019791  Haem peroxidase, animal type
 IPR034818  Dual oxidase 2
 IPR034821  Dual oxidase, peroxidase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002523 leukocyte migration involved in inflammatory response IMP
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0009611 response to wounding IMP
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0030593 neutrophil chemotaxis IMP
 biological_processGO:0048246 macrophage chemotaxis IMP
 biological_processGO:0050665 hydrogen peroxide biosynthetic process IMP
 biological_processGO:0050832 defense response to fungus IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016174 NAD(P)H oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Thyroxine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr