ENSMUSG00000033268


Mus musculus

Features
Gene ID: ENSMUSG00000033268
  
Biological name :Duox1
  
Synonyms : dual oxidase 1 / Duox1
  
Possible biological names infered from orthology : Q9NRD9
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 122315672
Gene end: 122347972
  
Corresponding Affymetrix probe sets: 10475456 (MoGene1.0st)   1456877_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097060
NCBI entrez gene - 99439     See in Manteia.
MGI - MGI:2139422
RefSeq - NM_001099297
RefSeq - XM_006500487
RefSeq Peptide - NP_001092767
swissprot - A2AQ92
Ensembl - ENSMUSG00000033268
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 duoxENSDARG00000062632Danio rerio
 ENSGALG00000041510Gallus gallus
 DUOX1ENSG00000137857Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Duox2 / dual oxidase 2 / Q9NRD8*ENSMUSG0000006845276
Cybb / Q61093 / Cytochrome b-245 heavy chain / P04839* / cytochrome b-245 beta chain*ENSMUSG0000001534011
Nox1 / Q8CIZ9 / NADPH oxidase 1 / Q9Y5S8*ENSMUSG0000003125711
Nox3 / Q672J9 / NADPH oxidase 3 / Q9HBY0*ENSMUSG0000002380210
Nox4 / Q9JHI8 / NADPH oxidase 4 / Q9NPH5*ENSMUSG0000003056210


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR010255  Haem peroxidase
 IPR011992  EF-hand domain pair
 IPR013112  FAD-binding 8
 IPR013121  Ferric reductase, NAD binding domain
 IPR013130  Ferric reductase transmembrane component-like domain
 IPR017927  Ferredoxin reductase-type FAD-binding domain
 IPR017938  Riboflavin synthase-like beta-barrel
 IPR018247  EF-Hand 1, calcium-binding site
 IPR019791  Haem peroxidase, animal type
 IPR029595  Dual oxidase 1/Duox
 IPR034821  Dual oxidase, peroxidase domain
 IPR037120  Haem peroxidase domain superfamily, animal type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0042335 cuticle development IEA
 biological_processGO:0050665 hydrogen peroxide biosynthetic process IEA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IGI
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016174 NAD(P)H oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0020037 heme binding IEA


Pathways (from Reactome)
Pathway description
Thyroxine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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