ENSDARG00000101324


Danio rerio
lipidtransporthdlapoa1bbindinginsulin-likegrowthfactorassemblyapolipoproteinelipoproteinmetabolicprocessextracellularregionplateletdegranulationabctransportershomeostasisscavengingclassbreceptorsregulationigfuptakeproteinsigfbpspost-translational

Features
Gene ID: ENSDARG00000101324
  
Biological name :apoa1b
  
Synonyms : apoa1b / apolipoprotein A-Ib
  
Possible biological names infered from orthology : APOA1 / apolipoprotein A1 / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I / P02647 / Q00623
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 102925
Gene end: 108414
  
Corresponding Affymetrix probe sets: Dr.1202.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000151245
Ensembl peptide - ENSDARP00000157033
Ensembl peptide - ENSDARP00000136446
NCBI entrez gene - 100101640     See in Manteia.
RefSeq - NM_001100144
RefSeq Peptide - NP_001093614
swissprot - A0A0R4IKF0
ZFIN ID - ZDB-GENE-050302-172
Ensembl - ENSDARG00000101324
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOA1ENSGALG00000007114Gallus gallus
 APOA1ENSG00000118137Homo sapiens
 Apoa1ENSMUSG00000032083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
apoa1a / O42363 / apolipoprotein A-Ia / APOA1* / Q00623* / P02647* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*ENSDARG0000001207638
apoa4b.2 / apolipoprotein A-IV b, tandem duplicate 2 / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * / Mus muscul...ENSDARG0000002086619
apoa4b.3 / apoa4b.2 / apolipoprotein A-IV b, tandem duplicate 3 / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * /...ENSDARG0000009492919
apoa4b.1 / apolipoprotein A-IV b, tandem duplicate 1 / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * / Mus muscul...ENSDARG0000004029818
apoa4a / apolipoprotein A-IV a / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * / Mus musculus apolipoprotein A-V ...ENSDARG0000010116016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000074  Apolipoprotein A/E


Gene Ontology (GO)
macromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationnitrogen compound metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationmacromolecule localizationestablishment of localizatioestablishment of localizationnitrogen compound metabolic nitrogen compound metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic organic substance metabolic process
lipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid bindinglipid binding
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0042157 lipoprotein metabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
ABC transporters in lipid homeostasis
Scavenging by Class B Receptors
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron assembly
HDL assembly
HDL clearance
HDL remodeling
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000012076 apoa1a / O42363 / apolipoprotein A-Ia / APOA1* / Q00623* / P02647* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*  / complex / reaction
 ENSDARG00000028071 bmp1a / bone morphogenetic protein 1a / BMP1* / P13497* / bone morphogenetic protein 1*  / reaction
 ENSDARG00000074635 abca1a / ATP-binding cassette, sub-family A (ABC1), member 1A / ABCA1* / P41233* / O95477* / ATP binding cassette subfamily A member 1* / ATP-binding cassette, sub-family A (ABC1), member 1*  / complex / reaction
 ENSDARG00000101324 apoa1b / apolipoprotein A-Ib / APOA1* / P02647* / apolipoprotein A1*  / complex / reaction






 

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