ENSDARG00000074635


Danio rerio

Features
Gene ID: ENSDARG00000074635
  
Biological name :abca1a
  
Synonyms : abca1a / ATP-binding cassette, sub-family A (ABC1), member 1A
  
Possible biological names infered from orthology : ABCA1 / ATP-binding cassette, sub-family A (ABC1), member 1 / ATP binding cassette subfamily A member 1 / O95477 / P41233
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 52560549
Gene end: 52628407
  
Corresponding Affymetrix probe sets: Dr.7365.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000132417
Ensembl peptide - ENSDARP00000114226
NCBI entrez gene - 558924     See in Manteia.
RefSeq - NM_001309465
RefSeq Peptide - NP_001296394
swissprot - B8A446
ZFIN ID - ZDB-GENE-031006-12
Ensembl - ENSDARG00000074635
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCA1ENSGALG00000015433Gallus gallus
 ABCA1ENSG00000165029Homo sapiens
 Abca1ENSMUSG00000015243Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abca4b / ATP-binding cassette, sub-family A (ABC1), member 4b / ABCA4* / P78363* / O35600* / ATP binding cassette subfamily A member 4* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSDARG0000006266151
abca4a / ATP-binding cassette, sub-family A (ABC1), member 4a / ABCA4* / P78363* / O35600* / ATP binding cassette subfamily A member 4* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSDARG0000005716950
abca2 / ATP-binding cassette, sub-family A (ABC1), member 2 / Q9BZC7* / ATP binding cassette subfamily A member 2*ENSDARG0000001350040
zgc:172302 / ABCA7* / Q8IZY2* / ATP binding cassette subfamily A member 7*ENSDARG0000007422128
abca12 / ATP-binding cassette, sub-family A (ABC1), member 12 / Q86UK0* / ATP binding cassette subfamily A member 12*ENSDARG0000007474928
abca3b / ATP-binding cassette, sub-family A (ABC1), member 3b / ABCA3* / Abca14* / Abca15* / Abca16* / Abca17* / E9PX95* / Q8R420* / Q99758* / ATP binding cassette subfamily A member 3* / A...ENSDARG0000010052428
abca5 / ATP-binding cassette, sub-family A (ABC1), member 5 / Q8K448* / Q8WWZ7* / ATP binding cassette subfamily A member 5*ENSDARG0000007404120


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002040 sprouting angiogenesis IGI
 biological_processGO:0010874 regulation of cholesterol efflux IGI
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
HDL assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000059125 prkacbb / protein kinase, cAMP-dependent, catalytic, beta b / P22694* / PRKACB* / protein kinase cAMP-activated catalytic subunit beta*  / reaction
 ENSDARG00000018508 zdhhc8b / zinc finger, DHHC-type containing 8b / Q9ULC8* / ZDHHC8* / Q5Y5T5* / zinc finger DHHC-type containing 8* / zinc finger, DHHC domain containing 8*  / reaction
 ENSDARG00000012076 apoa1a / O42363 / apolipoprotein A-Ia / APOA1* / Q00623* / P02647* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*  / complex / reaction
 ENSDARG00000074635 abca1a / ATP-binding cassette, sub-family A (ABC1), member 1A / ABCA1* / P41233* / O95477* / ATP binding cassette subfamily A member 1* / ATP-binding cassette, sub-family A (ABC1), member 1*  / complex
 ENSDARG00000101324 apoa1b / apolipoprotein A-Ib / APOA1* / P02647* / apolipoprotein A1*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr