ENSDARG00000074749


Danio rerio

Features
Gene ID: ENSDARG00000074749
  
Biological name :abca12
  
Synonyms : abca12 / ATP-binding cassette, sub-family A (ABC1), member 12
  
Possible biological names infered from orthology : ATP binding cassette subfamily A member 12 / Q86UK0
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 40685613
Gene end: 40765868
  
Corresponding Affymetrix probe sets: Dr.100.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000120698
swissprot - F1QLU8
ZFIN ID - ZDB-GENE-030131-9790
Ensembl - ENSDARG00000074749
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCA12ENSGALG00000003553Gallus gallus
 ABCA12ENSG00000144452Homo sapiens
 Abca12ENSMUSG00000050296Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abca2 / ATP-binding cassette, sub-family A (ABC1), member 2 / Q9BZC7* / ATP binding cassette subfamily A member 2*ENSDARG0000001350035
abca4b / ATP-binding cassette, sub-family A (ABC1), member 4b / ABCA4* / P78363* / O35600* / ATP binding cassette subfamily A member 4* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSDARG0000006266135
abca1a / ATP-binding cassette, sub-family A (ABC1), member 1A / ABCA1* / P41233* / O95477* / ATP binding cassette subfamily A member 1* / ATP-binding cassette, sub-family A (ABC1), member 1*ENSDARG0000007463535
abca4a / ATP-binding cassette, sub-family A (ABC1), member 4a / ABCA4* / P78363* / O35600* / ATP binding cassette subfamily A member 4* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSDARG0000005716934
abca3b / ATP-binding cassette, sub-family A (ABC1), member 3b / ABCA3* / Abca14* / Abca15* / Abca16* / Abca17* / E9PX95* / Q8R420* / Q99758* / ATP binding cassette subfamily A member 3* / A...ENSDARG0000010052428
abca5 / ATP-binding cassette, sub-family A (ABC1), member 5 / Q8K448* / Q8WWZ7* / ATP binding cassette subfamily A member 5*ENSDARG0000007404122
zgc:172302 / ABCA7* / Q8IZY2* / ATP binding cassette subfamily A member 7*ENSDARG0000007422116


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030371  ATP-binding cassette subfamily A member 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0048730 epidermis morphogenesis IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased size , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000105 epidermis epidermis morphology , abnormal
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 ZFA:0009158 keratinocyte keratinocyte cell surface disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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