ENSGALG00000003553


Gallus gallus

Features
Gene ID: ENSGALG00000003553
  
Biological name :ABCA12
  
Synonyms : ABCA12 / ATP binding cassette subfamily A member 12
  
Possible biological names infered from orthology : ATP-binding cassette, sub-family A (ABC1), member 12 / Q86UK0
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 4266827
Gene end: 4314212
  
Corresponding Affymetrix probe sets: GgaAffx.2211.1.S1_s_at (Chicken Array)   GgaAffx.2211.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005610
NCBI entrez gene - 424011     See in Manteia.
RefSeq - XM_015289303
RefSeq - XM_015289304
swissprot - E1C7T0
Ensembl - ENSGALG00000003553
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abca12ENSDARG00000074749Danio rerio
 ABCA12ENSG00000144452Homo sapiens
 Abca12ENSMUSG00000050296Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCA1 / ATP-binding cassette sub-family A member 1 / O95477* / P41233* / ATP binding cassette subfamily A member 1* / ATP-binding cassette, sub-family A (ABC1), member 1*ENSGALG0000001543332
ABCA7 / ATP binding cassette subfamily A member 7 / Q8IZY2* / Q91V24* / ATP-binding cassette, sub-family A (ABC1), member 7*ENSGALG0000000245331
ABCA4 / ATP binding cassette subfamily A member 4 / O35600* / P78363* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSGALG0000000575231
ABCA2 / ATP binding cassette subfamily A member 2 / Q9BZC7* / ATP-binding cassette, sub-family A (ABC1), member 2*ENSGALG0000003689430
ABCA3 / ATP binding cassette subfamily A member 3 / Abca17* / Abca14* / Abca15* / Abca16* / E9PX95* / Q8R420* / Q99758* / ATP-binding cassette, sub-family A (ABC1), member 3* / ATP-binding ...ENSGALG0000003783723
ABCA5 / ATP binding cassette subfamily A member 5 / Q8K448* / Q8WWZ7* / ATP-binding cassette, sub-family A (ABC1), member 5*ENSGALG0000000433318
ABCA13* / Q5SSE9* / Q86UQ4* / ATP binding cassette subfamily A member 13* / ATP-binding cassette, sub-family A (ABC1), member 13*ENSGALG0000001307917
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139917
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139516


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030371  ATP-binding cassette subfamily A member 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0010875 positive regulation of cholesterol efflux IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0031424 keratinization IEA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0033700 phospholipid efflux IEA
 biological_processGO:0035627 ceramide transport IEA
 biological_processGO:0043129 surfactant homeostasis IEA
 biological_processGO:0045055 regulated exocytosis IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0055088 lipid homeostasis IEA
 biological_processGO:0061436 establishment of skin barrier IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:2000010 positive regulation of protein localization to cell surface IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 cellular_componentGO:0097209 epidermal lamellar body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005319 lipid transporter activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0034191 apolipoprotein A-I receptor binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
ABC transporters in lipid homeostasis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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