ENSGALG00000015433


Gallus gallus

Features
Gene ID: ENSGALG00000015433
  
Biological name :ABCA1
  
Synonyms : ABCA1 / ATP-binding cassette sub-family A member 1
  
Possible biological names infered from orthology : ATP-binding cassette, sub-family A (ABC1), member 1 / ATP binding cassette subfamily A member 1 / O95477 / P41233
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 54725868
Gene end: 54817218
  
Corresponding Affymetrix probe sets: Gga.102.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024845
NCBI entrez gene - 373945     See in Manteia.
RefSeq - NM_204145
RefSeq Peptide - NP_989476
swissprot - E1C619
Ensembl - ENSGALG00000015433
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abca1aENSDARG00000074635Danio rerio
 ABCA1ENSG00000165029Homo sapiens
 Abca1ENSMUSG00000015243Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCA7 / ATP binding cassette subfamily A member 7 / Q8IZY2* / Q91V24* / ATP-binding cassette, sub-family A (ABC1), member 7*ENSGALG0000000245357
ABCA4 / ATP binding cassette subfamily A member 4 / O35600* / P78363* / ATP-binding cassette, sub-family A (ABC1), member 4*ENSGALG0000000575250
ABCA2 / ATP binding cassette subfamily A member 2 / Q9BZC7* / ATP-binding cassette, sub-family A (ABC1), member 2*ENSGALG0000003689440
ABCA12 / ATP binding cassette subfamily A member 12 / Q86UK0* / ATP-binding cassette, sub-family A (ABC1), member 12*ENSGALG0000000355331
ABCA3 / ATP binding cassette subfamily A member 3 / Abca17* / Abca14* / Abca15* / Abca16* / E9PX95* / Q8R420* / Q99758* / ATP-binding cassette, sub-family A (ABC1), member 3* / ATP-binding ...ENSGALG0000003783728
ABCA5 / ATP binding cassette subfamily A member 5 / Q8K448* / Q8WWZ7* / ATP-binding cassette, sub-family A (ABC1), member 5*ENSGALG0000000433319
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139919
ABCA8* / ABCA9* / ABCA6* / ABCA10* / Abca8a* / Abca8b* / O94911* / Q8IUA7* / Q8K440* / Q8K441* / Q8K442* / Q8K449* / Q8N139* / Q8WWZ4* / ATP binding cassette subfamily A member 6* / ATP bin...ENSGALG0000002139517
ABCA13* / Q5SSE9* / Q86UQ4* / ATP binding cassette subfamily A member 13* / ATP-binding cassette, sub-family A (ABC1), member 13*ENSGALG0000001307915


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR017871  ABC transporter, conserved site
 IPR026082  ABC transporter A
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002790 peptide secretion IEA
 biological_processGO:0006497 protein lipidation IEA
 biological_processGO:0006869 lipid transport IBA
 biological_processGO:0006911 phagocytosis, engulfment IEA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0010875 positive regulation of cholesterol efflux IEA
 biological_processGO:0016197 endosomal transport IEA
 biological_processGO:0032367 intracellular cholesterol transport IEA
 biological_processGO:0032489 regulation of Cdc42 protein signal transduction IEA
 biological_processGO:0033344 cholesterol efflux IEA
 biological_processGO:0033700 phospholipid efflux IEA
 biological_processGO:0034380 high-density lipoprotein particle assembly IEA
 biological_processGO:0034616 response to laminar fluid shear stress IEA
 biological_processGO:0038027 apolipoprotein A-I-mediated signaling pathway IEA
 biological_processGO:0042157 lipoprotein metabolic process IEA
 biological_processGO:0042158 lipoprotein biosynthetic process IEA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0043691 reverse cholesterol transport IEA
 biological_processGO:0045332 phospholipid translocation IEA
 biological_processGO:0050702 interleukin-1 beta secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0055091 phospholipid homeostasis IEA
 biological_processGO:0060155 platelet dense granule organization IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071404 cellular response to low-density lipoprotein particle stimulus IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0045335 phagocytic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005548 phospholipid transporter activity IEA
 molecular_functionGO:0008509 anion transmembrane transporter activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0017127 cholesterol transporter activity IEA
 molecular_functionGO:0019905 syntaxin binding IEA
 molecular_functionGO:0031267 small GTPase binding IEA
 molecular_functionGO:0034185 apolipoprotein binding IEA
 molecular_functionGO:0034186 apolipoprotein A-I binding IEA
 molecular_functionGO:0034188 apolipoprotein A-I receptor activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:0090554 phosphatidylcholine-translocating ATPase activity IEA
 molecular_functionGO:0090556 phosphatidylserine-translocating ATPase activity IEA


Pathways (from Reactome)
Pathway description
HDL assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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