ENSDARG00000102978


Danio rerio

Features
Gene ID: ENSDARG00000102978
  
Biological name :eif4a3
  
Synonyms : eif4a3 / eukaryotic translation initiation factor 4A3
  
Possible biological names infered from orthology : Eukaryotic initiation factor 4A-III Eukaryotic initiation factor 4A-III, N-terminally processed / Gm5580 / Gm8994 / P38919 / Q91VC3
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 44878571
Gene end: 44898129
  
Corresponding Affymetrix probe sets: Dr.1756.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000135974
swissprot - A0A0R4IKW3
ZFIN ID - ZDB-GENE-040426-915
Ensembl - ENSDARG00000102978
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF4A3ENSGALG00000008530Gallus gallus
 EIF4A3ENSG00000141543Homo sapiens
 Eif4a3ENSMUSG00000025580Mus musculus
 Gm5580ENSMUSG00000107906Mus musculus
 Gm8994ENSMUSG00000094973Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif4a2 / eukaryotic translation initiation factor 4A, isoform 2 / P10630* / Q14240* / eukaryotic translation initiation factor 4A2* / Mus musculus eukaryotic translation initiation factor 4...ENSDARG0000001647767
eif4a1a / eukaryotic translation initiation factor 4A1A / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*ENSDARG0000009211566
eif4a1b / eukaryotic translation initiation factor 4A1B / EIF4A1* / P60842* / P60843* / Eukaryotic initiation factor 4A-I * / eukaryotic translation initiation factor 4A1*ENSDARG0000000303265


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of Mature mRNA derived from an Intron-Containing Transcript
Deadenylation of mRNA
mRNA Splicing - Major Pathway
mRNA 3-end processing
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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