ENSMUSG00000107906


Mus musculus

Features
Gene ID: ENSMUSG00000107906
  
Biological name :Gm5580
  
Synonyms : Gm5580
  
Possible biological names infered from orthology : EIF4A3 / eukaryotic translation initiation factor 4A3 / P38919
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: E3
Gene start: 116551141
Gene end: 116552502
  
Corresponding Affymetrix probe sets: 10539177 (MoGene1.0st)   10541067 (MoGene1.0st)   1417242_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145194
MGI - MGI:3646594
swissprot - A0A0N4SVP8
Ensembl - ENSMUSG00000107906
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif4a3ENSDARG00000102978Danio rerio
 EIF4A3ENSGALG00000008530Gallus gallus
 EIF4A3ENSG00000141543Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm8994 / EIF4A3* / P38919* / eukaryotic translation initiation factor 4A3*ENSMUSG0000009497398
Eif4a3 / Q91VC3 / Eukaryotic initiation factor 4A-III Eukaryotic initiation factor 4A-III, N-terminally processed / P38919* / eukaryotic translation initiation factor 4A3*ENSMUSG0000002558097
Eif4a2 / P10630 / Mus musculus eukaryotic translation initiation factor 4A2 (Eif4a2), transcript variant 5, mRNA.ENSMUSG0000002288466
Eif4a1 / P60843 / Eukaryotic initiation factor 4A-I / P60842* / eukaryotic translation initiation factor 4A1*ENSMUSG0000005979665


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
ISG15 antiviral mechanism
Transport of Mature mRNA derived from an Intron-Containing Transcript
Deadenylation of mRNA
mRNA Splicing - Major Pathway
mRNA 3-end processing
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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