ENSG00000016490


Homo sapiens

Features
Gene ID: ENSG00000016490
  
Biological name :CLCA1
  
Synonyms : A8K7I4 / chloride channel accessory 1 / CLCA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.3
Gene start: 86468368
Gene end: 86500289
  
Corresponding Affymetrix probe sets: 210107_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000234701
Ensembl peptide - ENSP00000378200
NCBI entrez gene - 1179     See in Manteia.
OMIM - 603906
RefSeq - NM_001285
RefSeq Peptide - NP_001276
swissprot - A8K7I4
Ensembl - ENSG00000016490
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clca1ENSDARG00000100941Danio rerio
 clca1ENSDARG00000016290Danio rerio
 clca5.1ENSDARG00000099606Danio rerio
 si:ch211-116o3.3ENSDARG00000086498Danio rerio
 ENSGALG00000006322Gallus gallus
 Clca1ENSMUSG00000028255Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLCA4 / Q14CN2 / chloride channel accessory 4ENSG0000001660261
CLCA2 / Q9UQC9 / chloride channel accessory 2ENSG0000013797544


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR004727  Calcium-activated chloride channel protein, chordata
 IPR013642  Calcium-activated chloride channel, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0042589 zymogen granule membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0005229 intracellular calcium activated chloride channel activity IBA
 molecular_functionGO:0005254 chloride channel activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr