ENSG00000137975


Homo sapiens

Features
Gene ID: ENSG00000137975
  
Biological name :CLCA2
  
Synonyms : chloride channel accessory 2 / CLCA2 / Q9UQC9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.3
Gene start: 86424086
Gene end: 86456558
  
Corresponding Affymetrix probe sets: 206164_at (Human Genome U133 Plus 2.0 Array)   206165_s_at (Human Genome U133 Plus 2.0 Array)   206166_s_at (Human Genome U133 Plus 2.0 Array)   217528_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359596
NCBI entrez gene - 9635     See in Manteia.
OMIM - 604003
RefSeq - NM_006536
RefSeq - XM_011542448
RefSeq Peptide - NP_006527
swissprot - Q9UQC9
Ensembl - ENSG00000137975
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clca1ENSDARG00000100941Danio rerio
 clca1ENSDARG00000016290Danio rerio
 clca5.1ENSDARG00000099606Danio rerio
 si:ch211-116o3.3ENSDARG00000086498Danio rerio
 Clca2ENSMUSG00000036960Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLCA1 / A8K7I4 / chloride channel accessory 1ENSG0000001649042
CLCA4 / Q14CN2 / chloride channel accessory 4ENSG0000001660242


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR004727  Calcium-activated chloride channel protein, chordata
 IPR013642  Calcium-activated chloride channel, N-terminal
 IPR013783  Immunoglobulin-like fold
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009925 basal plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0005229 intracellular calcium activated chloride channel activity IBA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0015276 ligand-gated ion channel activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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