ENSG00000101890


Homo sapiens

Features
Gene ID: ENSG00000101890
  
Biological name :GUCY2F
  
Synonyms : guanylate cyclase 2F, retinal / GUCY2F / P51841
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q23
Gene start: 109372906
Gene end: 109482072
  
Corresponding Affymetrix probe sets: 208053_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000218006
NCBI entrez gene - 2986     See in Manteia.
OMIM - 300041
RefSeq - NM_001522
RefSeq Peptide - NP_001513
swissprot - P51841
Ensembl - ENSG00000101890
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gc2ENSDARG00000018329Danio rerio
 ENSGALG00000000808Gallus gallus
 Gucy2fENSMUSG00000042282Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GUCY2D / Q02846 / guanylate cyclase 2D, retinalENSG0000013251850
NPR2 / P20594 / natriuretic peptide receptor 2ENSG0000015989932
NPR1 / P16066 / natriuretic peptide receptor 1ENSG0000016941831
GUCY2C / P25092 / guanylate cyclase 2CENSG0000007001930
P33402 / GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2ENSG0000015240216
Q02108 / GUCY1A1 / guanylate cyclase 1 soluble subunit alpha 1ENSG0000016411614
Q02153 / GUCY1B1 / guanylate cyclase 1 soluble subunit beta 1ENSG0000006191813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR011645  Haem NO binding associated
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase
 IPR033484  Retinal guanylyl cyclase 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway TAS
 biological_processGO:0007601 visual perception TAS
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0022400 regulation of rhodopsin mediated signaling pathway TAS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050908 detection of light stimulus involved in visual perception IEA
 cellular_componentGO:0005640 nuclear outer membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097381 photoreceptor disc membrane TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity TAS
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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