ENSG00000109851


Homo sapiens

Features
Gene ID: ENSG00000109851
  
Biological name :DBX1
  
Synonyms : A6NMT0 / DBX1 / developing brain homeobox 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.1
Gene start: 20156155
Gene end: 20160613
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000436881
NCBI entrez gene - 120237     See in Manteia.
RefSeq - NM_001029865
RefSeq Peptide - NP_001025036
swissprot - A6NMT0
Ensembl - ENSG00000109851
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dbx1aENSDARG00000086393Danio rerio
 dbx1bENSDARG00000001859Danio rerio
 DBX1ENSGALG00000003965Gallus gallus
 Dbx1ENSMUSG00000030507Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DBX2 / Q6ZNG2 / developing brain homeobox 2ENSG0000018561034
HLX / Q14774 / H2.0 like homeoboxENSG0000013663032
NKX6-1 / P78426 / NK6 homeobox 1ENSG0000016362322
BARX2 / Q9UMQ3 / BARX homeobox 2ENSG0000004303918
HHEX / Q03014 / hematopoietically expressed homeoboxENSG0000015280418
BARX1 / Q9HBU1 / BARX homeobox 1ENSG0000013166817
BARHL2 / Q9NY43 / BarH like homeobox 2ENSG0000014303217
NKX6-2 / Q9C056 / NK6 homeobox 2ENSG0000014882617
TLX3 / O43711 / T cell leukemia homeobox 3ENSG0000016443817
BARHL1 / Q9BZE3 / BarH like homeobox 1ENSG0000012549216
LBX1 / P52954 / ladybird homeobox 1ENSG0000013813616
TLX1 / P31314 / T cell leukemia homeobox 1ENSG0000010780715
BSX / Q3C1V8 / brain specific homeoboxENSG0000018890915
TLX2 / O43763 / T cell leukemia homeobox 2ENSG0000011529714
LBX2 / Q6XYB7 / ladybird homeobox 2ENSG0000017952813
A6NJ46 / NKX6-3 / NK6 homeobox 3ENSG000001650668


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0021521 ventral spinal cord interneuron specification IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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