ENSG00000144481


Homo sapiens

Features
Gene ID: ENSG00000144481
  
Biological name :TRPM8
  
Synonyms : Q7Z2W7 / transient receptor potential cation channel subfamily M member 8 / TRPM8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 233917398
Gene end: 234019522
  
Corresponding Affymetrix probe sets: 220226_at (Human Genome U133 Plus 2.0 Array)   243483_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386771
Ensembl peptide - ENSP00000390609
Ensembl peptide - ENSP00000414198
Ensembl peptide - ENSP00000404423
Ensembl peptide - ENSP00000396745
Ensembl peptide - ENSP00000323926
Ensembl peptide - ENSP00000347956
NCBI entrez gene - 79054     See in Manteia.
OMIM - 606678
RefSeq - XM_017004891
RefSeq - NM_024080
RefSeq - XM_011511810
RefSeq Peptide - NP_076985
swissprot - H0Y7P0
swissprot - H7BZP4
swissprot - A0A1L1Z822
swissprot - Q7Z2W7
swissprot - W8DTH1
swissprot - A0A0C4DFT0
swissprot - F8WD55
swissprot - A0A0A0MSV2
Ensembl - ENSG00000144481
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRPM8ENSGALG00000004116Gallus gallus
 Trpm8ENSMUSG00000036251Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRPM2 / O94759 / transient receptor potential cation channel subfamily M member 2ENSG0000014218543
TRPM4 / Q8TD43 / transient receptor potential cation channel subfamily M member 4ENSG0000013052933
TRPM5 / Q9NZQ8 / transient receptor potential cation channel subfamily M member 5ENSG0000007098532
TRPM3 / Q9HCF6 / transient receptor potential cation channel subfamily M member 3ENSG0000008306729
TRPM1 / Q7Z4N2 / transient receptor potential cation channel subfamily M member 1ENSG0000013416028
TRPM7 / Q96QT4 / transient receptor potential cation channel subfamily M member 7ENSG0000009243926
TRPM6 / Q9BX84 / transient receptor potential cation channel subfamily M member 6ENSG0000011912126


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR029603  Transient receptor potential cation channel subfamily M member 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0009266 response to temperature stimulus IEA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0016048 detection of temperature stimulus IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050951 sensory perception of temperature stimulus IEA
 biological_processGO:0050955 thermoception IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070207 protein homotrimerization IEA
 biological_processGO:0070588 calcium ion transmembrane transport TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005262 calcium channel activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr