ENSG00000148602


Homo sapiens
membraneLRIT1leucine-richrepeatsubtypeimmunoglobulindomainsuperfamilyendoplasmicreticulumfibronectintypeiiiintegralcomponentcysteine-richflankingregionc-terminaltypicali-setfoldbiologicalprocessmolecularfunctionproteinbinding

Features
Gene ID: ENSG00000148602
  
Biological name :LRIT1
  
Synonyms : leucine rich repeat, Ig-like and transmembrane domains 1 / LRIT1 / Q9P2V4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q23.1
Gene start: 84231593
Gene end: 84241461
  
Corresponding Affymetrix probe sets: 211353_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361177
NCBI entrez gene - 26103     See in Manteia.
OMIM - 616103
RefSeq - NM_015613
RefSeq - XM_011539623
RefSeq Peptide - NP_056428
swissprot - Q9P2V4
Ensembl - ENSG00000148602
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrit1aENSDARG00000019179Danio rerio
 lrit1bENSDARG00000099406Danio rerio
 LRIT1ENSGALG00000002303Gallus gallus
 Lrit1ENSMUSG00000041044Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRIT3 / Q3SXY7 / leucine rich repeat, Ig-like and transmembrane domains 3ENSG0000018342335
LRIT2 / A6NDA9 / leucine rich repeat, Ig-like and transmembrane domains 2ENSG0000020403325
ISLR2 / Q6UXK2 / immunoglobulin superfamily containing leucine rich repeat 2ENSG0000016717821
ISLR / O14498 / immunoglobulin superfamily containing leucine rich repeatENSG0000012900915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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